Intergenerational epigenetic inheritance of cancer susceptibility in mammals
Susceptibility to cancer is heritable, but much of this heritability remains unexplained. Some ‘missing’ heritability may be mediated by epigenetic changes in the parental germ line that do not involve transmission of genetic variants from parent to offspring. We report that deletion of the chromati...
Main Authors: | Bluma J Lesch, Zuzana Tothova, Elizabeth A Morgan, Zhicong Liao, Roderick T Bronson, Benjamin L Ebert, David C Page |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/39380 |
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