Monoclonal Antibodies Targeting Alarmins: A New Perspective for Biological Therapies of Severe Asthma

Monoclonal Antibodies Targeting Alarmins: A New Perspective for Biological Therapies of Severe Asthma

Alarmins are innate cytokines, including thymic stromal lymphopoietin (TSLP), interleukin-33 (IL-33), and interleukin-25 (IL-25), which are mainly produced by airway epithelium and exert a prominent role in asthma pathobiology. In particular, several environmental factors such as allergens, cigarett...

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Bibliographic Details
Main Authors: Corrado Pelaia, Giulia Pelaia, Federico Longhini, Claudia Crimi, Cecilia Calabrese, Luca Gallelli, Angela Sciacqua, Alessandro Vatrella
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
asthma
TSLP
IL-33
IL-25
tezepelumab
anti-alarmins
Online Access:https://www.mdpi.com/2227-9059/9/9/1108

Internet

https://www.mdpi.com/2227-9059/9/9/1108

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