Measuring Absolute RNA Copy Numbers at High Temporal Resolution Reveals Transcriptome Kinetics in Development

Transcript regulation is essential for cell function, and misregulation can lead to disease. Despite technologies to survey the transcriptome, we lack a comprehensive understanding of transcript kinetics, which limits quantitative biology. This is an acute challenge in embryonic development, where r...

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Bibliographic Details
Main Authors: Nick D.L. Owens, Ira L. Blitz, Maura A. Lane, Ilya Patrushev, John D. Overton, Michael J. Gilchrist, Ken W.Y. Cho, Mustafa K. Khokha
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715014916