Effect of Noscapine on Drug Resistance of 5-Fluorouracil-resistant Human Colon Cancer Cell Lines HT-29/5-Fu, LoVo/5-Fu and SW480/5-Fu

Effect of Noscapine on Drug Resistance of 5-Fluorouracil-resistant Human Colon Cancer Cell Lines HT-29/5-Fu, LoVo/5-Fu and SW480/5-Fu

Objective To investigate the effect of Noscapine(Nos) on drug resistance of 5-Fu-resistant human colon cancer cell lines and its mechanism. Methods Drug-resistant cell lines HT-29/5-Fu, LoVo/5-Fu and SW480/5-Fu were established. MTT assay was used to test IC50 and cell morphology was observed. Cell...

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Bibliographic Details
Main Authors: HAN Zheng, HUANG Xiaodong, LIU Meng, ZHU Qingxi, TAN Jie, LIU Weijie, CHEN Wei, ZOU Yanli, CAI Yishan, HUANG Shasha, TIAN Xia
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2019-08-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
noscapine
colon cancer
drug resistant cell
p38
resistance-related protein
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1927.htm

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