STAT6 signaling pathway controls germinal center responses promoted after antigen targeting to conventional type 2 dendritic cells

STAT6 signaling pathway controls germinal center responses promoted after antigen targeting to conventional type 2 dendritic cells

Conventional dendritic cells (cDCs) are antigen-presenting cells specialized in naïve T cell priming. Mice splenic cDCs are classified as cDC1s and cDC2s, and their main functions have been elucidated in the last decade. While cDC1s are specialized in priming type 1 helper T cells (TH1) and in cross...

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Bibliographic Details
Main Authors: Fernando Bandeira Sulczewski, Larissa Alves Martino, Bianca da Silva Almeida, Márcio Massao Yamamoto, Daniela Santoro Rosa, Silvia Beatriz Boscardin
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Immunology
Subjects:
Dendritic cells
Antigen targeting
DCIR2
Germinal center
Plasma cells
T follicular helper cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2590255521000135

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