The Relationship between Coronary Artery Movement Type and Stenosis Severity with Acute Myocardial Infarction
Introduction: The severity of coronary artery stenosis which leads to myocardial infarction (MI) has been a matter of controversy. Historical data are in favor of mild luminal stenosis (<50% diameter stenosis) while recent studies suggest hemodynamically-significant coronary stenosis as the main...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2013-07-01
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| Series: | Journal of Cardiovascular and Thoracic Research |
| Subjects: | |
| Online Access: | http://journals.tbzmed.ac.ir/JCVTR/PDF/JCVTR-5-41.pdf |
| _version_ | 1811259165579935744 |
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| author | Samad Ghaffari Siamak Erfanparast Ahmad Separham Sepideh Sokhanvar Mehrdad Yavarikia Leili Pourafkari |
| author_facet | Samad Ghaffari Siamak Erfanparast Ahmad Separham Sepideh Sokhanvar Mehrdad Yavarikia Leili Pourafkari |
| author_sort | Samad Ghaffari |
| collection | DOAJ |
| description | Introduction: The severity of coronary artery stenosis which leads to myocardial infarction (MI) has been a matter of controversy. Historical data are in favor of mild luminal stenosis (<50% diameter stenosis) while recent studies suggest hemodynamically-significant coronary stenosis as the main substrate for subsequent MI. Also, mechanical stress resulted from coronary artery movement (CAM) may be responsible for plaques rupture. In this study, we evaluated the severity of plaques leading to MI and common CAM patterns in the involved coronary segments.
Methods: In a cross-sectional descriptive-analytical study, on patients with acute ST-segment myocardial infarction (STEMI) undergoing coronary angiography, the relationship between coronary artery movement type and stenosis severity with acute MI was evaluated. Lesions with stenosis diameter greater than 50 percent were defined as moderate and those equal or higher than 70% were defined as severe stenosis. Three different patterns of coronary artery motion including compression, bending and displacement types were evaluated in segments with culprit lesion.
Results: One hundred and sixty two patients were enrolled. Ninety patients (55.6%) were male and 72 (44.4%) were female. Mean age of the patients was 60.56±13.43 years. In terms of Infarct related lesions (IRLs), 86% of the cases had at least moderate stenosis and in 67%, severe stenosis was present. More than 50% stenosis was found in all patients with anterior STEMI involving LAD. Among three types of coronary motion patterns, compression pattern was significantly higher in LAD (P<0.001), RCA (P<0.001), Diagonal artery (P<0.001) and OM branch (P=0.044), but not in proper LCX (P=0.307).
Conclusion: Most of the lesions leading to myocardial infarction have a diameter stenosis of at least 50% and mainly are located in the coronary segments with compression movement pattern. |
| first_indexed | 2024-04-12T18:26:22Z |
| format | Article |
| id | doaj.art-74308457fd204a688d07be40b8baa7bf |
| institution | Directory Open Access Journal |
| issn | 2008-5117 2008-6830 |
| language | English |
| last_indexed | 2024-04-12T18:26:22Z |
| publishDate | 2013-07-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Cardiovascular and Thoracic Research |
| spelling | doaj.art-74308457fd204a688d07be40b8baa7bf2022-12-22T03:21:13ZengTabriz University of Medical SciencesJournal of Cardiovascular and Thoracic Research2008-51172008-68302013-07-0152414410.5681/jcvtr.2013.009JCVTR_20130714090816The Relationship between Coronary Artery Movement Type and Stenosis Severity with Acute Myocardial InfarctionSamad Ghaffari0Siamak Erfanparast1Ahmad Separham2Sepideh Sokhanvar3Mehrdad Yavarikia4Leili Pourafkari5Cardiovascular Research Center, Tabriz University of Medical sciences, Tabriz, IranCardiovascular Research Center, Tabriz University of Medical sciences, Tabriz, IranCardiovascular Research Center, Tabriz University of Medical sciences, Tabriz, IranDepartment of Cardiology, Zanjan University of Medical sciences, Zanjan, IranCardiovascular Research Center, Tabriz University of Medical sciences, Tabriz, IranCardiovascular Research Center, Tabriz University of Medical sciences, Tabriz, IranIntroduction: The severity of coronary artery stenosis which leads to myocardial infarction (MI) has been a matter of controversy. Historical data are in favor of mild luminal stenosis (<50% diameter stenosis) while recent studies suggest hemodynamically-significant coronary stenosis as the main substrate for subsequent MI. Also, mechanical stress resulted from coronary artery movement (CAM) may be responsible for plaques rupture. In this study, we evaluated the severity of plaques leading to MI and common CAM patterns in the involved coronary segments. Methods: In a cross-sectional descriptive-analytical study, on patients with acute ST-segment myocardial infarction (STEMI) undergoing coronary angiography, the relationship between coronary artery movement type and stenosis severity with acute MI was evaluated. Lesions with stenosis diameter greater than 50 percent were defined as moderate and those equal or higher than 70% were defined as severe stenosis. Three different patterns of coronary artery motion including compression, bending and displacement types were evaluated in segments with culprit lesion. Results: One hundred and sixty two patients were enrolled. Ninety patients (55.6%) were male and 72 (44.4%) were female. Mean age of the patients was 60.56±13.43 years. In terms of Infarct related lesions (IRLs), 86% of the cases had at least moderate stenosis and in 67%, severe stenosis was present. More than 50% stenosis was found in all patients with anterior STEMI involving LAD. Among three types of coronary motion patterns, compression pattern was significantly higher in LAD (P<0.001), RCA (P<0.001), Diagonal artery (P<0.001) and OM branch (P=0.044), but not in proper LCX (P=0.307). Conclusion: Most of the lesions leading to myocardial infarction have a diameter stenosis of at least 50% and mainly are located in the coronary segments with compression movement pattern.http://journals.tbzmed.ac.ir/JCVTR/PDF/JCVTR-5-41.pdfMyocardial InfarctionCoronary Artery MovementCoronary Plaque |
| spellingShingle | Samad Ghaffari Siamak Erfanparast Ahmad Separham Sepideh Sokhanvar Mehrdad Yavarikia Leili Pourafkari The Relationship between Coronary Artery Movement Type and Stenosis Severity with Acute Myocardial Infarction Journal of Cardiovascular and Thoracic Research Myocardial Infarction Coronary Artery Movement Coronary Plaque |
| title | The Relationship between Coronary Artery Movement Type and Stenosis Severity with Acute Myocardial Infarction |
| title_full | The Relationship between Coronary Artery Movement Type and Stenosis Severity with Acute Myocardial Infarction |
| title_fullStr | The Relationship between Coronary Artery Movement Type and Stenosis Severity with Acute Myocardial Infarction |
| title_full_unstemmed | The Relationship between Coronary Artery Movement Type and Stenosis Severity with Acute Myocardial Infarction |
| title_short | The Relationship between Coronary Artery Movement Type and Stenosis Severity with Acute Myocardial Infarction |
| title_sort | relationship between coronary artery movement type and stenosis severity with acute myocardial infarction |
| topic | Myocardial Infarction Coronary Artery Movement Coronary Plaque |
| url | http://journals.tbzmed.ac.ir/JCVTR/PDF/JCVTR-5-41.pdf |
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