An exosome mRNA-related gene risk model to evaluate the tumor microenvironment and predict prognosis in hepatocellular carcinoma

An exosome mRNA-related gene risk model to evaluate the tumor microenvironment and predict prognosis in hepatocellular carcinoma

Abstract Background The interplay between exosomes and the tumor microenvironment (TME) remains unclear. We investigated the influence of exosomes on the TME in hepatocellular carcinoma (HCC), focusing on their mRNA expression profile. Methods mRNA expression profiles of exosomes were obtained from...

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Bibliographic Details
Main Authors: Zhonghai Du, Xiuchen Han, Liping Zhu, Li Li, Leandro Castellano, Justin Stebbing, Ling Peng, Zhiqiang Wang
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Medical Genomics
Subjects:
Hepatocellular carcinoma
Extracellular vesicle
Exosome
Risk score
Prognostic signature
Tumor immune microenvironment
Online Access:https://doi.org/10.1186/s12920-024-01865-z

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