CHARACTERISTICS OF THE CORONARY ARTERIAL LESIONS IN YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
OBJECTIVES: To assess characteristics of coronary arterial lesion (CAL) by means of invasive coronary angiography in young patients, aged <35 years, who sustained acute myocardial infarction (AMI). METHODS: This prospective study of one-year duration was conducted from December 2009 to Novembe...
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| Format: | Article |
| Language: | English |
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Khyber Medical University
2018-06-01
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| Series: | Khyber Medical University Journal |
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| Online Access: | http://www.kmuj.kmu.edu.pk/article/view/17588/pdf |
| _version_ | 1818994063914827776 |
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| author | Lubna Noor Yasir Adnan Muhammad Habeel Dar Umair Ali Farooq Ahmad Zahid Aslam Awan |
| author_facet | Lubna Noor Yasir Adnan Muhammad Habeel Dar Umair Ali Farooq Ahmad Zahid Aslam Awan |
| author_sort | Lubna Noor |
| collection | DOAJ |
| description | OBJECTIVES: To assess characteristics of coronary arterial lesion (CAL) by means of invasive coronary angiography in young patients, aged <35 years, who sustained acute myocardial infarction (AMI).
METHODS: This prospective study of one-year duration was conducted from December 2009 to November 2010 at the cardiology departments of three teaching hospitals in Peshawar, Pakistan. All patients aged <35 years, evaluated angiographically after an AMI, were included. The individual CAL were characterized.
RESULTS: About 101 patients with AMI underwent coronary angiography. Mean age of the patients was 32.56±3.26 years (range 22–35 years). Out of 101 patients, 86 (78.18%) were males, while 15 (21.81%) were females. On coronary angiography, there were 25 (24.8%) patients with non-atherosclerotic coronary arteries, 39 (38.6%) with single vessel disease (SVD), 18 (17.8%) had double vessel disease (DVD), and 19 (18.8%) had triple vessel disease (TVD). Of the total, 3 patients (2.97%) had disease in the left main stem. One hundred thirty-two lesions (39x1=39 in SVD; 18x2=36 in DVD & 19x3=57 in TVD) were studied. The lesions were mostly discrete to tubular with less diffuse involvement and had either no or mild calcification. Thrombus was found in 5 patients with SVD (12.82%), 2 with DVD (11.11%) and 1 with TVD (1.75%).
CONCLUSION: This study shows that young (age <35 years) patients who have sustained AMI, have less extensive coronary artery disease but complex morphologic features. There was a higher incidence of normal vessels on coronary angiography with a very few cases of left main coronary arterial involvement. |
| first_indexed | 2024-12-20T20:52:00Z |
| format | Article |
| id | doaj.art-74340f5ea43d413b8d4793a8bc887b29 |
| institution | Directory Open Access Journal |
| issn | 2305-2643 2305-2651 |
| language | English |
| last_indexed | 2024-12-20T20:52:00Z |
| publishDate | 2018-06-01 |
| publisher | Khyber Medical University |
| record_format | Article |
| series | Khyber Medical University Journal |
| spelling | doaj.art-74340f5ea43d413b8d4793a8bc887b292022-12-21T19:26:54ZengKhyber Medical UniversityKhyber Medical University Journal2305-26432305-26512018-06-0110028185CHARACTERISTICS OF THE CORONARY ARTERIAL LESIONS IN YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTIONLubna Noor0Yasir Adnan1Muhammad Habeel Dar2Umair Ali3Farooq Ahmad4Zahid Aslam Awan5Assistant Professor Cardiology, Lady Reading Hospital, Peshawar, PakistanSenior Registrar Cardiology, Rehman Medical Institute, Peshawar, PakistanCardiologist, Moulvee Ameer Shah Hospital, Peshawar, PakistanCardiologist, Moulvee Ameer Shah Hospital, Peshawar, PakistanAssistant Professor, Khyber Teaching Hospital, Peshawar, PakistanProfessor of Cardiology, Hayatabad Medical Complex Peshawar, PakistanOBJECTIVES: To assess characteristics of coronary arterial lesion (CAL) by means of invasive coronary angiography in young patients, aged <35 years, who sustained acute myocardial infarction (AMI). METHODS: This prospective study of one-year duration was conducted from December 2009 to November 2010 at the cardiology departments of three teaching hospitals in Peshawar, Pakistan. All patients aged <35 years, evaluated angiographically after an AMI, were included. The individual CAL were characterized. RESULTS: About 101 patients with AMI underwent coronary angiography. Mean age of the patients was 32.56±3.26 years (range 22–35 years). Out of 101 patients, 86 (78.18%) were males, while 15 (21.81%) were females. On coronary angiography, there were 25 (24.8%) patients with non-atherosclerotic coronary arteries, 39 (38.6%) with single vessel disease (SVD), 18 (17.8%) had double vessel disease (DVD), and 19 (18.8%) had triple vessel disease (TVD). Of the total, 3 patients (2.97%) had disease in the left main stem. One hundred thirty-two lesions (39x1=39 in SVD; 18x2=36 in DVD & 19x3=57 in TVD) were studied. The lesions were mostly discrete to tubular with less diffuse involvement and had either no or mild calcification. Thrombus was found in 5 patients with SVD (12.82%), 2 with DVD (11.11%) and 1 with TVD (1.75%). CONCLUSION: This study shows that young (age <35 years) patients who have sustained AMI, have less extensive coronary artery disease but complex morphologic features. There was a higher incidence of normal vessels on coronary angiography with a very few cases of left main coronary arterial involvement.http://www.kmuj.kmu.edu.pk/article/view/17588/pdfMyocardial InfarctionCoronary Artery DiseaseCoronary arterial lesionsCoronary AngiographyAtherosclerosis |
| spellingShingle | Lubna Noor Yasir Adnan Muhammad Habeel Dar Umair Ali Farooq Ahmad Zahid Aslam Awan CHARACTERISTICS OF THE CORONARY ARTERIAL LESIONS IN YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION Khyber Medical University Journal Myocardial Infarction Coronary Artery Disease Coronary arterial lesions Coronary Angiography Atherosclerosis |
| title | CHARACTERISTICS OF THE CORONARY ARTERIAL LESIONS IN YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION |
| title_full | CHARACTERISTICS OF THE CORONARY ARTERIAL LESIONS IN YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION |
| title_fullStr | CHARACTERISTICS OF THE CORONARY ARTERIAL LESIONS IN YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION |
| title_full_unstemmed | CHARACTERISTICS OF THE CORONARY ARTERIAL LESIONS IN YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION |
| title_short | CHARACTERISTICS OF THE CORONARY ARTERIAL LESIONS IN YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION |
| title_sort | characteristics of the coronary arterial lesions in young patients with acute myocardial infarction |
| topic | Myocardial Infarction Coronary Artery Disease Coronary arterial lesions Coronary Angiography Atherosclerosis |
| url | http://www.kmuj.kmu.edu.pk/article/view/17588/pdf |
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