The role of nanotechnology in current COVID-19 outbreak
COVID-19 has recently become one of the most challenging pandemics of the last century with deadly outcomes and a high rate of reproduction number. It emphasizes the critical need for the designing of efficient vaccines to prevent virus infection, early and fast diagnosis by the high sensitivity and...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-04-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844021009440 |
| _version_ | 1818643219117768704 |
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| author | Shima Tavakol Masoumeh Zahmatkeshan Reza Mohammadinejad Saeed Mehrzadi Mohammad T. Joghataei Mo S. Alavijeh Alexander Seifalian |
| author_facet | Shima Tavakol Masoumeh Zahmatkeshan Reza Mohammadinejad Saeed Mehrzadi Mohammad T. Joghataei Mo S. Alavijeh Alexander Seifalian |
| author_sort | Shima Tavakol |
| collection | DOAJ |
| description | COVID-19 has recently become one of the most challenging pandemics of the last century with deadly outcomes and a high rate of reproduction number. It emphasizes the critical need for the designing of efficient vaccines to prevent virus infection, early and fast diagnosis by the high sensitivity and selectivity diagnostic kits, and effective antiviral and protective therapeutics to decline and eliminate the viral load and side effects derived from tissue damages. Therefore, non-toxic antiviral nanoparticles (NPs) have been under development for clinical application to prevent and treat COVID-19. NPs showed great promise to provide nano vaccines against viral infections. Here, we discuss the potentials of NPs that may be applied as a drug itself or as a platform for the aim of drug and vaccine repurposing and development. Meanwhile, the advanced strategies based on NPs to detect viruses will be described with the goal of encouraging scientists to design effective and cost-benefit nanoplatforms for prevention, diagnosis, and treatment. |
| first_indexed | 2024-12-16T23:55:28Z |
| format | Article |
| id | doaj.art-74393e13a42a4879882916a786525fd4 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-12-16T23:55:28Z |
| publishDate | 2021-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-74393e13a42a4879882916a786525fd42022-12-21T22:11:13ZengElsevierHeliyon2405-84402021-04-0174e06841The role of nanotechnology in current COVID-19 outbreakShima Tavakol0Masoumeh Zahmatkeshan1Reza Mohammadinejad2Saeed Mehrzadi3Mohammad T. Joghataei4Mo S. Alavijeh5Alexander Seifalian6Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran; Pharmidex Pharmaceutical Services Ltd., London, United Kingdom; Corresponding author.Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran; Department of Medical Nanotechnology, Iran University of Medical Sciences, Tehran, IranResearch Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, IranRazi Drug Research Center, Iran University of Medical Sciences, Tehran, IranCellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran; Department of Neuroscience, Iran University of Medical Sciences, Tehran, IranPharmidex Pharmaceutical Services Ltd., London, United KingdomNanotechnology and Regenerative Medicine Commercialization Centre (NanoRegMed Ltd, UK), London BioScience Innovation Centre, London, NW1 0NH, United Kingdom; Corresponding author.COVID-19 has recently become one of the most challenging pandemics of the last century with deadly outcomes and a high rate of reproduction number. It emphasizes the critical need for the designing of efficient vaccines to prevent virus infection, early and fast diagnosis by the high sensitivity and selectivity diagnostic kits, and effective antiviral and protective therapeutics to decline and eliminate the viral load and side effects derived from tissue damages. Therefore, non-toxic antiviral nanoparticles (NPs) have been under development for clinical application to prevent and treat COVID-19. NPs showed great promise to provide nano vaccines against viral infections. Here, we discuss the potentials of NPs that may be applied as a drug itself or as a platform for the aim of drug and vaccine repurposing and development. Meanwhile, the advanced strategies based on NPs to detect viruses will be described with the goal of encouraging scientists to design effective and cost-benefit nanoplatforms for prevention, diagnosis, and treatment.http://www.sciencedirect.com/science/article/pii/S2405844021009440COVID-19NanoparticleDrug repurposingVaccineNanocarrierCoronavirus |
| spellingShingle | Shima Tavakol Masoumeh Zahmatkeshan Reza Mohammadinejad Saeed Mehrzadi Mohammad T. Joghataei Mo S. Alavijeh Alexander Seifalian The role of nanotechnology in current COVID-19 outbreak Heliyon COVID-19 Nanoparticle Drug repurposing Vaccine Nanocarrier Coronavirus |
| title | The role of nanotechnology in current COVID-19 outbreak |
| title_full | The role of nanotechnology in current COVID-19 outbreak |
| title_fullStr | The role of nanotechnology in current COVID-19 outbreak |
| title_full_unstemmed | The role of nanotechnology in current COVID-19 outbreak |
| title_short | The role of nanotechnology in current COVID-19 outbreak |
| title_sort | role of nanotechnology in current covid 19 outbreak |
| topic | COVID-19 Nanoparticle Drug repurposing Vaccine Nanocarrier Coronavirus |
| url | http://www.sciencedirect.com/science/article/pii/S2405844021009440 |
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