Analysis of CDKN1C in fetal growth restriction and pregnancy loss [version 1; peer review: 2 approved]
Background: Cyclin-dependent kinase inhibitor 1C (CDKN1C) is a key negative regulator of cell growth encoded by a paternally imprinted/maternally expressed gene in humans. Loss-of-function variants in CDKN1C are associated with an overgrowth condition (Beckwith-Wiedemann Syndrome) whereas “gain-of-f...
Main Authors: | Jenifer P. Suntharalingham, Miho Ishida, Federica Buonocore, Ignacio del Valle, Nita Solanky, Charalambos Demetriou, Lesley Regan, Gudrun E. Moore, John C. Achermann |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2019-01-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/8-90/v1 |
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