Research progress in atopic dermatitis and microbe therapy
The pathogenesis of AD has not been fully elucidated, and it is currently recognized that it is related to genetic and environmental factors, skin barrier dysfunction and immune dysregulation dominated by type 2 inflammation. In recent years, with the in-depth study of intestinal microbiota, microbe...
| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
2023-10-01
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| Series: | Pifu-xingbing zhenliaoxue zazhi |
| Subjects: | |
| Online Access: | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2023.05.011 |
| _version_ | 1797374023776075776 |
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| author | Yijia RUAN Mingjun HOU Yunsheng LIANG |
| author_facet | Yijia RUAN Mingjun HOU Yunsheng LIANG |
| author_sort | Yijia RUAN |
| collection | DOAJ |
| description | The pathogenesis of AD has not been fully elucidated, and it is currently recognized that it is related to genetic and environmental factors, skin barrier dysfunction and immune dysregulation dominated by type 2 inflammation. In recent years, with the in-depth study of intestinal microbiota, microbe therapy may make up for the shortage of topical glucocorticoids and other treatments. This article focuses on the relationship of the changes in microecology with the pathogenesis of AD, elaborates the important role of intestinal microbiota, cutaneous microbiota and their metabolites in AD, and reviews the research progress in microbe therapy, so as to provide new enlightenment for the treatment of AD. |
| first_indexed | 2024-03-08T18:59:53Z |
| format | Article |
| id | doaj.art-743f25991b964c17ad0076c252de29f6 |
| institution | Directory Open Access Journal |
| issn | 1674-8468 |
| language | zho |
| last_indexed | 2024-03-08T18:59:53Z |
| publishDate | 2023-10-01 |
| publisher | editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology |
| record_format | Article |
| series | Pifu-xingbing zhenliaoxue zazhi |
| spelling | doaj.art-743f25991b964c17ad0076c252de29f62023-12-28T06:54:48Zzhoeditoiral office of Journal of Diagnosis and Therapy on Dermato-venereologyPifu-xingbing zhenliaoxue zazhi1674-84682023-10-0130544845410.3969/j.issn.1674-8468.2023.05.011Research progress in atopic dermatitis and microbe therapyYijia RUANMingjun HOUYunsheng LIANGThe pathogenesis of AD has not been fully elucidated, and it is currently recognized that it is related to genetic and environmental factors, skin barrier dysfunction and immune dysregulation dominated by type 2 inflammation. In recent years, with the in-depth study of intestinal microbiota, microbe therapy may make up for the shortage of topical glucocorticoids and other treatments. This article focuses on the relationship of the changes in microecology with the pathogenesis of AD, elaborates the important role of intestinal microbiota, cutaneous microbiota and their metabolites in AD, and reviews the research progress in microbe therapy, so as to provide new enlightenment for the treatment of AD.http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2023.05.011atopic dermatitiscutaneous microbiotaintestinal microbiotamicrobe therapy |
| spellingShingle | Yijia RUAN Mingjun HOU Yunsheng LIANG Research progress in atopic dermatitis and microbe therapy Pifu-xingbing zhenliaoxue zazhi atopic dermatitis cutaneous microbiota intestinal microbiota microbe therapy |
| title | Research progress in atopic dermatitis and microbe therapy |
| title_full | Research progress in atopic dermatitis and microbe therapy |
| title_fullStr | Research progress in atopic dermatitis and microbe therapy |
| title_full_unstemmed | Research progress in atopic dermatitis and microbe therapy |
| title_short | Research progress in atopic dermatitis and microbe therapy |
| title_sort | research progress in atopic dermatitis and microbe therapy |
| topic | atopic dermatitis cutaneous microbiota intestinal microbiota microbe therapy |
| url | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2023.05.011 |
| work_keys_str_mv | AT yijiaruan researchprogressinatopicdermatitisandmicrobetherapy AT mingjunhou researchprogressinatopicdermatitisandmicrobetherapy AT yunshengliang researchprogressinatopicdermatitisandmicrobetherapy |