A novel four-component route to synthesis 11-amino-12-(4-aryl)-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ol derivatives

A series of chromeno[2,3-b]quinolinol derivatives were synthesized through one-pot four-component reaction of resorcinol, malononitrile, aromatic aldehydes and cyclohexanone using iron(III) triflate Fe(OTf)3, under solvent-free and ultrasonic irradiation conditions. The products were afforded in goo...

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Main Author: Saman Damavandi
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535211002425
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author Saman Damavandi
author_facet Saman Damavandi
author_sort Saman Damavandi
collection DOAJ
description A series of chromeno[2,3-b]quinolinol derivatives were synthesized through one-pot four-component reaction of resorcinol, malononitrile, aromatic aldehydes and cyclohexanone using iron(III) triflate Fe(OTf)3, under solvent-free and ultrasonic irradiation conditions. The products were afforded in good to excellent yields. The advantages of this method are the use of an inexpensive and readily available catalyst, short reaction time, easy workup and improved yields.
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spelling doaj.art-743f83865b794d3b82d274b3d127b85d2022-12-22T02:51:03ZengElsevierArabian Journal of Chemistry1878-53522016-11-019S2S941S94510.1016/j.arabjc.2011.09.001A novel four-component route to synthesis 11-amino-12-(4-aryl)-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ol derivativesSaman DamavandiA series of chromeno[2,3-b]quinolinol derivatives were synthesized through one-pot four-component reaction of resorcinol, malononitrile, aromatic aldehydes and cyclohexanone using iron(III) triflate Fe(OTf)3, under solvent-free and ultrasonic irradiation conditions. The products were afforded in good to excellent yields. The advantages of this method are the use of an inexpensive and readily available catalyst, short reaction time, easy workup and improved yields.http://www.sciencedirect.com/science/article/pii/S1878535211002425Chromeno[2,3-b]quinolinolFour componentOne-potFe(OTf)3
spellingShingle Saman Damavandi
A novel four-component route to synthesis 11-amino-12-(4-aryl)-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ol derivatives
Arabian Journal of Chemistry
Chromeno[2,3-b]quinolinol
Four component
One-pot
Fe(OTf)3
title A novel four-component route to synthesis 11-amino-12-(4-aryl)-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ol derivatives
title_full A novel four-component route to synthesis 11-amino-12-(4-aryl)-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ol derivatives
title_fullStr A novel four-component route to synthesis 11-amino-12-(4-aryl)-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ol derivatives
title_full_unstemmed A novel four-component route to synthesis 11-amino-12-(4-aryl)-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ol derivatives
title_short A novel four-component route to synthesis 11-amino-12-(4-aryl)-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ol derivatives
title_sort novel four component route to synthesis 11 amino 12 4 aryl 8 9 10 12 tetrahydro 7h chromeno 2 3 b quinolin 3 ol derivatives
topic Chromeno[2,3-b]quinolinol
Four component
One-pot
Fe(OTf)3
url http://www.sciencedirect.com/science/article/pii/S1878535211002425
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