Specific Fluorescent Probes for Imaging DNA in Cell-Free Solution and in Mitochondria in Living Cells

Specific Fluorescent Probes for Imaging DNA in Cell-Free Solution and in Mitochondria in Living Cells

New styryl dyes consisting of N-methylpyridine or N-methylquinoline scaffolds were synthesized, and their binding affinities for DNA in cell-free solution were studied. The replacement of heterocyclic residue from the pyridine to quinoline group as well as variation in the phenyl part strongly influ...

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Bibliographic Details
Main Authors: Anna S. Efimova, Mariya A. Ustimova, Nelly S. Chmelyuk, Maxim A. Abakumov, Yury V. Fedorov, Olga A. Fedorova
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biosensors
Subjects:
styryl dyes
fluorescence probe
DNA binding
mitochondrial selectivity
Online Access:https://www.mdpi.com/2079-6374/13/7/734

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