Antibiotic Resistance in Pacific Island Countries and Territories: A Systematic Scoping Review
Several studies have investigated antimicrobial resistance in low- and middle-income countries, but to date little attention has been paid to the Pacific Islands Countries and Territories (PICTs). This study aims to review the literature on antibiotic resistance (ABR) in healthcare settings in PICTs...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-03-01
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| Series: | Antibiotics |
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| Online Access: | http://www.mdpi.com/2079-6382/8/1/29 |
| _version_ | 1818148662510878720 |
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| author | Nicola D. Foxlee Nicola Townell Lachlan McIver Colleen L. Lau |
| author_facet | Nicola D. Foxlee Nicola Townell Lachlan McIver Colleen L. Lau |
| author_sort | Nicola D. Foxlee |
| collection | DOAJ |
| description | Several studies have investigated antimicrobial resistance in low- and middle-income countries, but to date little attention has been paid to the Pacific Islands Countries and Territories (PICTs). This study aims to review the literature on antibiotic resistance (ABR) in healthcare settings in PICTs to inform further research and future policy development for the region. Following the PRISMA-ScR checklist health databases and grey literature sources were searched. Three reviewers independently screened the literature for inclusion, data was extracted using a charting tool and the results were described and synthesised. Sixty-five studies about ABR in PICTs were identified and these are primarily about New Caledonia, Fiji and Papua New Guinea. Ten PICTs contributed the remaining 21 studies and nine PICTs were not represented. The predominant gram-positive pathogen reported was community-acquired methicillin resistant S. aureus and the rates of resistance ranged widely (>50% to <20%). Resistance reported in gram-negative pathogens was mainly associated with healthcare-associated infections (HCAIs). Extended spectrum beta-lactamase (ESBL) producing K. pneumoniae isolates were reported in New Caledonia (3.4%) and Fiji (22%) and carbapenem resistant A. baumannii (CR-ab) isolates in the French Territories (24.8%). ABR is a problem in the PICTs, but the epidemiology requires further characterisation. Action on strengthening surveillance in PICTs needs to be prioritised so strategies to contain ABR can be fully realised. |
| first_indexed | 2024-12-11T12:54:42Z |
| format | Article |
| id | doaj.art-744791f8525b4b5485a368346c231c77 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-12-11T12:54:42Z |
| publishDate | 2019-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-744791f8525b4b5485a368346c231c772022-12-22T01:06:37ZengMDPI AGAntibiotics2079-63822019-03-01812910.3390/antibiotics8010029antibiotics8010029Antibiotic Resistance in Pacific Island Countries and Territories: A Systematic Scoping ReviewNicola D. Foxlee0Nicola Townell1Lachlan McIver2Colleen L. Lau3Department of Global Health, Research School of Population Health, Australian National University, Canberra ACT 2600, AustraliaDiagnostic Microbiology Development Program, Phnom Penh 12000, CambodiaMédecins Sans Frontières, 1202 Geneva, SwitzerlandDepartment of Global Health, Research School of Population Health, Australian National University, Canberra ACT 2600, AustraliaSeveral studies have investigated antimicrobial resistance in low- and middle-income countries, but to date little attention has been paid to the Pacific Islands Countries and Territories (PICTs). This study aims to review the literature on antibiotic resistance (ABR) in healthcare settings in PICTs to inform further research and future policy development for the region. Following the PRISMA-ScR checklist health databases and grey literature sources were searched. Three reviewers independently screened the literature for inclusion, data was extracted using a charting tool and the results were described and synthesised. Sixty-five studies about ABR in PICTs were identified and these are primarily about New Caledonia, Fiji and Papua New Guinea. Ten PICTs contributed the remaining 21 studies and nine PICTs were not represented. The predominant gram-positive pathogen reported was community-acquired methicillin resistant S. aureus and the rates of resistance ranged widely (>50% to <20%). Resistance reported in gram-negative pathogens was mainly associated with healthcare-associated infections (HCAIs). Extended spectrum beta-lactamase (ESBL) producing K. pneumoniae isolates were reported in New Caledonia (3.4%) and Fiji (22%) and carbapenem resistant A. baumannii (CR-ab) isolates in the French Territories (24.8%). ABR is a problem in the PICTs, but the epidemiology requires further characterisation. Action on strengthening surveillance in PICTs needs to be prioritised so strategies to contain ABR can be fully realised.http://www.mdpi.com/2079-6382/8/1/29antimicrobial resistancegram-negative organismsgram-positive organismssurveillancehealthcare associated infections |
| spellingShingle | Nicola D. Foxlee Nicola Townell Lachlan McIver Colleen L. Lau Antibiotic Resistance in Pacific Island Countries and Territories: A Systematic Scoping Review Antibiotics antimicrobial resistance gram-negative organisms gram-positive organisms surveillance healthcare associated infections |
| title | Antibiotic Resistance in Pacific Island Countries and Territories: A Systematic Scoping Review |
| title_full | Antibiotic Resistance in Pacific Island Countries and Territories: A Systematic Scoping Review |
| title_fullStr | Antibiotic Resistance in Pacific Island Countries and Territories: A Systematic Scoping Review |
| title_full_unstemmed | Antibiotic Resistance in Pacific Island Countries and Territories: A Systematic Scoping Review |
| title_short | Antibiotic Resistance in Pacific Island Countries and Territories: A Systematic Scoping Review |
| title_sort | antibiotic resistance in pacific island countries and territories a systematic scoping review |
| topic | antimicrobial resistance gram-negative organisms gram-positive organisms surveillance healthcare associated infections |
| url | http://www.mdpi.com/2079-6382/8/1/29 |
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