Exposure to Atmospheric Ozone Disruption and Altitude Over 3500 m.a.s.l. are Associated with a Higher Prevalence of Photodermatoses in Pediatric Population of High-Altitude in Peru
Willy Ramos,1,2 Ericson L Gutierrez,1,3 Jhony A De La Cruz-Vargas,1 Jesús Díaz,4 Jorge Hurtado,2 Gerardo Ronceros,2 Esther de Vries5 1Instituto de Investigaciones en Ciencias Biomédicas (INICIB), Universidad Ricardo Palma, Lima, Perú; 2Instituto de Investigaciones Clínicas, Universidad Nacional Mayo...
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| Format: | Article |
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Dove Medical Press
2022-08-01
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| Series: | Clinical, Cosmetic and Investigational Dermatology |
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| Online Access: | https://www.dovepress.com/exposure-to-atmospheric-ozone-disruption-and-altitude-over-3500-masl-a-peer-reviewed-fulltext-article-CCID |
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| author | Ramos W Gutierrez EL De La Cruz-Vargas JA Díaz J Hurtado J Ronceros G de Vries E |
| author_facet | Ramos W Gutierrez EL De La Cruz-Vargas JA Díaz J Hurtado J Ronceros G de Vries E |
| author_sort | Ramos W |
| collection | DOAJ |
| description | Willy Ramos,1,2 Ericson L Gutierrez,1,3 Jhony A De La Cruz-Vargas,1 Jesús Díaz,4 Jorge Hurtado,2 Gerardo Ronceros,2 Esther de Vries5 1Instituto de Investigaciones en Ciencias Biomédicas (INICIB), Universidad Ricardo Palma, Lima, Perú; 2Instituto de Investigaciones Clínicas, Universidad Nacional Mayor de San Marcos, Lima, Perú; 3Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Perú; 4Universidad Católica Santo Toribio de Mogrovejo, Chiclayo, Perú; 5Departamento de Epidemiologia Clínica y Bioestadística, Pontificia Universidad Javeriana, Bogotá, ColombiaCorrespondence: Willy Ramos, Instituto de Investigaciones en Ciencias Biomédicas (INICIB), Universidad Ricardo Palma, Av. Alfredo Benavides 5440, Santiago de Surco, Lima, 15039, Perú, Email willymh98@hotmail.comObjective: To determine if exposure to atmospheric ozone disruption and other factors are associated with photodermatoses in the high-altitude pediatric population in Peru.Materials and Methods: A cross-sectional study based on data obtained from studies of dermatological diseases among the population exposed to mine tailings in Peru which included children under the age of 18 in 6 population centers located over 2500 meters above sea level (m.a.s.l). We evaluated the presence of photodermatoses and possible associated factors obtaining the adjusted odds ratio (aOR) and confidence intervals (CI).Results: 594 children below the age of 18 participated in this study, 53.0% girls, the average age was 10.4 ± 4.1 years. 51.3% were exposed to a mini hole in the ozone layer, 60.1% resided at an altitude over 3500 m.a.s.l and 51.9% presented cutaneous manifestations of atopy upon physical examination. The prevalence of photodermatoses was 64.8%, of which the most frequent were actinic prurigo (49.3%), pityriasis alba (18.5%) and actinic cheilitis (4.4%). The multivariate analysis found that residing in a region exposed to the mini hole in the ozone layer (aOR = 4.23; CI 95%: 2.32– 7.72) and residing at an altitude over 3500 m.a.s.l (aOR = 2.76; CI 95%: 1.57– 4.86) were both independent associated factors to photodermatoses.Conclusion: A high prevalence of photodermatoses exists among the pediatric population living at high-altitude in Peru. Residing in a region exposed to a mini hole in the ozone layer and residing over 3500 m.a.s.l constituted associated factors.Keywords: ultraviolet rays, ozone depletion, high-altitude, children, adolescents |
| first_indexed | 2024-12-10T11:57:12Z |
| format | Article |
| id | doaj.art-7447d3cbda96477c8719d302dead0225 |
| institution | Directory Open Access Journal |
| issn | 1178-7015 |
| language | English |
| last_indexed | 2024-12-10T11:57:12Z |
| publishDate | 2022-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical, Cosmetic and Investigational Dermatology |
| spelling | doaj.art-7447d3cbda96477c8719d302dead02252022-12-22T01:49:45ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152022-08-01Volume 151779178677833Exposure to Atmospheric Ozone Disruption and Altitude Over 3500 m.a.s.l. are Associated with a Higher Prevalence of Photodermatoses in Pediatric Population of High-Altitude in PeruRamos WGutierrez ELDe La Cruz-Vargas JADíaz JHurtado JRonceros Gde Vries EWilly Ramos,1,2 Ericson L Gutierrez,1,3 Jhony A De La Cruz-Vargas,1 Jesús Díaz,4 Jorge Hurtado,2 Gerardo Ronceros,2 Esther de Vries5 1Instituto de Investigaciones en Ciencias Biomédicas (INICIB), Universidad Ricardo Palma, Lima, Perú; 2Instituto de Investigaciones Clínicas, Universidad Nacional Mayor de San Marcos, Lima, Perú; 3Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Perú; 4Universidad Católica Santo Toribio de Mogrovejo, Chiclayo, Perú; 5Departamento de Epidemiologia Clínica y Bioestadística, Pontificia Universidad Javeriana, Bogotá, ColombiaCorrespondence: Willy Ramos, Instituto de Investigaciones en Ciencias Biomédicas (INICIB), Universidad Ricardo Palma, Av. Alfredo Benavides 5440, Santiago de Surco, Lima, 15039, Perú, Email willymh98@hotmail.comObjective: To determine if exposure to atmospheric ozone disruption and other factors are associated with photodermatoses in the high-altitude pediatric population in Peru.Materials and Methods: A cross-sectional study based on data obtained from studies of dermatological diseases among the population exposed to mine tailings in Peru which included children under the age of 18 in 6 population centers located over 2500 meters above sea level (m.a.s.l). We evaluated the presence of photodermatoses and possible associated factors obtaining the adjusted odds ratio (aOR) and confidence intervals (CI).Results: 594 children below the age of 18 participated in this study, 53.0% girls, the average age was 10.4 ± 4.1 years. 51.3% were exposed to a mini hole in the ozone layer, 60.1% resided at an altitude over 3500 m.a.s.l and 51.9% presented cutaneous manifestations of atopy upon physical examination. The prevalence of photodermatoses was 64.8%, of which the most frequent were actinic prurigo (49.3%), pityriasis alba (18.5%) and actinic cheilitis (4.4%). The multivariate analysis found that residing in a region exposed to the mini hole in the ozone layer (aOR = 4.23; CI 95%: 2.32– 7.72) and residing at an altitude over 3500 m.a.s.l (aOR = 2.76; CI 95%: 1.57– 4.86) were both independent associated factors to photodermatoses.Conclusion: A high prevalence of photodermatoses exists among the pediatric population living at high-altitude in Peru. Residing in a region exposed to a mini hole in the ozone layer and residing over 3500 m.a.s.l constituted associated factors.Keywords: ultraviolet rays, ozone depletion, high-altitude, children, adolescentshttps://www.dovepress.com/exposure-to-atmospheric-ozone-disruption-and-altitude-over-3500-masl-a-peer-reviewed-fulltext-article-CCIDultraviolet raysozone depletionhigh-altitudechildrenadolescents. |
| spellingShingle | Ramos W Gutierrez EL De La Cruz-Vargas JA Díaz J Hurtado J Ronceros G de Vries E Exposure to Atmospheric Ozone Disruption and Altitude Over 3500 m.a.s.l. are Associated with a Higher Prevalence of Photodermatoses in Pediatric Population of High-Altitude in Peru Clinical, Cosmetic and Investigational Dermatology ultraviolet rays ozone depletion high-altitude children adolescents. |
| title | Exposure to Atmospheric Ozone Disruption and Altitude Over 3500 m.a.s.l. are Associated with a Higher Prevalence of Photodermatoses in Pediatric Population of High-Altitude in Peru |
| title_full | Exposure to Atmospheric Ozone Disruption and Altitude Over 3500 m.a.s.l. are Associated with a Higher Prevalence of Photodermatoses in Pediatric Population of High-Altitude in Peru |
| title_fullStr | Exposure to Atmospheric Ozone Disruption and Altitude Over 3500 m.a.s.l. are Associated with a Higher Prevalence of Photodermatoses in Pediatric Population of High-Altitude in Peru |
| title_full_unstemmed | Exposure to Atmospheric Ozone Disruption and Altitude Over 3500 m.a.s.l. are Associated with a Higher Prevalence of Photodermatoses in Pediatric Population of High-Altitude in Peru |
| title_short | Exposure to Atmospheric Ozone Disruption and Altitude Over 3500 m.a.s.l. are Associated with a Higher Prevalence of Photodermatoses in Pediatric Population of High-Altitude in Peru |
| title_sort | exposure to atmospheric ozone disruption and altitude over 3500 m a s l are associated with a higher prevalence of photodermatoses in pediatric population of high altitude in peru |
| topic | ultraviolet rays ozone depletion high-altitude children adolescents. |
| url | https://www.dovepress.com/exposure-to-atmospheric-ozone-disruption-and-altitude-over-3500-masl-a-peer-reviewed-fulltext-article-CCID |
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