Omics-Driven Biotechnology for Industrial Applications
Biomanufacturing is a key component of biotechnology that uses biological systems to produce bioproducts of commercial relevance, which are of great interest to the energy, material, pharmaceutical, food, and agriculture industries. Biotechnology-based approaches, such as synthetic biology and metab...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-02-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2021.613307/full |
| _version_ | 1818411411562299392 |
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| author | Bashar Amer Bashar Amer Edward E. K. Baidoo Edward E. K. Baidoo Edward E. K. Baidoo |
| author_facet | Bashar Amer Bashar Amer Edward E. K. Baidoo Edward E. K. Baidoo Edward E. K. Baidoo |
| author_sort | Bashar Amer |
| collection | DOAJ |
| description | Biomanufacturing is a key component of biotechnology that uses biological systems to produce bioproducts of commercial relevance, which are of great interest to the energy, material, pharmaceutical, food, and agriculture industries. Biotechnology-based approaches, such as synthetic biology and metabolic engineering are heavily reliant on “omics” driven systems biology to characterize and understand metabolic networks. Knowledge gained from systems biology experiments aid the development of synthetic biology tools and the advancement of metabolic engineering studies toward establishing robust industrial biomanufacturing platforms. In this review, we discuss recent advances in “omics” technologies, compare the pros and cons of the different “omics” technologies, and discuss the necessary requirements for carrying out multi-omics experiments. We highlight the influence of “omics” technologies on the production of biofuels and bioproducts by metabolic engineering. Finally, we discuss the application of “omics” technologies to agricultural and food biotechnology, and review the impact of “omics” on current COVID-19 research. |
| first_indexed | 2024-12-14T10:30:59Z |
| format | Article |
| id | doaj.art-7449d43eebc045d1a7d3eb1c464ae7db |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-12-14T10:30:59Z |
| publishDate | 2021-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-7449d43eebc045d1a7d3eb1c464ae7db2022-12-21T23:06:08ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852021-02-01910.3389/fbioe.2021.613307613307Omics-Driven Biotechnology for Industrial ApplicationsBashar Amer0Bashar Amer1Edward E. K. Baidoo2Edward E. K. Baidoo3Edward E. K. Baidoo4Lawrence Berkeley National Laboratory, Joint BioEnergy Institute, Emeryville, CA, United StatesBiological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, CA, United StatesLawrence Berkeley National Laboratory, Joint BioEnergy Institute, Emeryville, CA, United StatesBiological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, CA, United StatesU.S. Department of Energy, Agile BioFoundry, Emeryville, CA, United StatesBiomanufacturing is a key component of biotechnology that uses biological systems to produce bioproducts of commercial relevance, which are of great interest to the energy, material, pharmaceutical, food, and agriculture industries. Biotechnology-based approaches, such as synthetic biology and metabolic engineering are heavily reliant on “omics” driven systems biology to characterize and understand metabolic networks. Knowledge gained from systems biology experiments aid the development of synthetic biology tools and the advancement of metabolic engineering studies toward establishing robust industrial biomanufacturing platforms. In this review, we discuss recent advances in “omics” technologies, compare the pros and cons of the different “omics” technologies, and discuss the necessary requirements for carrying out multi-omics experiments. We highlight the influence of “omics” technologies on the production of biofuels and bioproducts by metabolic engineering. Finally, we discuss the application of “omics” technologies to agricultural and food biotechnology, and review the impact of “omics” on current COVID-19 research.https://www.frontiersin.org/articles/10.3389/fbioe.2021.613307/fullsystems biologygenomicstranscriptomicsmetabolomicsproteomicsmulti-omics |
| spellingShingle | Bashar Amer Bashar Amer Edward E. K. Baidoo Edward E. K. Baidoo Edward E. K. Baidoo Omics-Driven Biotechnology for Industrial Applications Frontiers in Bioengineering and Biotechnology systems biology genomics transcriptomics metabolomics proteomics multi-omics |
| title | Omics-Driven Biotechnology for Industrial Applications |
| title_full | Omics-Driven Biotechnology for Industrial Applications |
| title_fullStr | Omics-Driven Biotechnology for Industrial Applications |
| title_full_unstemmed | Omics-Driven Biotechnology for Industrial Applications |
| title_short | Omics-Driven Biotechnology for Industrial Applications |
| title_sort | omics driven biotechnology for industrial applications |
| topic | systems biology genomics transcriptomics metabolomics proteomics multi-omics |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2021.613307/full |
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