Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: study protocol for a systematic guideline review
Introduction Atherosclerotic cardiovascular disease (ASCVD) was the main cause of death in Germany in 2021, with major risk factors (ie, hypertension, diabetes, dyslipidaemia, obesity and certain lifestyle factors) being highly prevalent. Preventing ASCVD by assessment and modification of these risk...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2023-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/12/e074788.full |
| _version_ | 1827394230767583232 |
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| author | Veronika van der Wardt Christiane Muth Lara Schürmann Maren Bredehorst Ana I González-González Svetlana Puzhko Joerg Haasenritter |
| author_facet | Veronika van der Wardt Christiane Muth Lara Schürmann Maren Bredehorst Ana I González-González Svetlana Puzhko Joerg Haasenritter |
| author_sort | Veronika van der Wardt |
| collection | DOAJ |
| description | Introduction Atherosclerotic cardiovascular disease (ASCVD) was the main cause of death in Germany in 2021, with major risk factors (ie, hypertension, diabetes, dyslipidaemia, obesity and certain lifestyle factors) being highly prevalent. Preventing ASCVD by assessment and modification of these risk factors is an important challenge for general practitioners. This study aims to systematically review and synthesise recent recommendations of national and international guidelines regarding the primary prevention of ASCVD in adults in primary care.Methods and analysis We will conduct a systematic review of clinical practice guidelines (CPGs) to evaluate primary prevention strategies for ASCVD. CPGs will be retrieved from MEDLINE and the Turning Research Into Practice database, guideline-specific databases and websites of guidelines-producing societies, with searches limited to publications from 2016 onwards. We will include CPGs in English, Spanish, German or Dutch languages that provide evidence-based recommendations for ASCVD prevention. The study population will include adults without diagnosed ASCVD. Two independent reviewers will assess guideline eligibility and quality by means of the mini-checklist MiChe, and extract study characteristics and relevant recommendations for further consistency analysis. A third reviewer will resolve disagreements. Findings will be presented as a narrative synthesis and in tabular form.Ethics and dissemination This review does not require ethical approval. Our systematic review will inform the CPG of the German College of General Practitioners and Family Physicians on the primary prevention of ASCVD. The review results will also be disseminated through publications in peer-reviewed journals and presentations at local, national and international conferences.PROSPERO registration number CRD42023394605. |
| first_indexed | 2024-03-08T18:07:31Z |
| format | Article |
| id | doaj.art-7449e59f8b104ea685beef5645a84c21 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-03-08T18:07:31Z |
| publishDate | 2023-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-7449e59f8b104ea685beef5645a84c212024-01-01T14:10:06ZengBMJ Publishing GroupBMJ Open2044-60552023-12-01131210.1136/bmjopen-2023-074788Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: study protocol for a systematic guideline reviewVeronika van der Wardt0Christiane Muth1Lara Schürmann2Maren Bredehorst3Ana I González-González4Svetlana Puzhko5Joerg Haasenritter6Department of Primary Care, University of Marburg, Marburg, GermanyDepartment of General Practice and Family Medicine, University Bielefeld, Bielefeld, GermanyDepartment of General Practice and Family Medicine, University Bielefeld, Bielefeld, GermanyDepartment of Primary Care, University of Marburg, Marburg, GermanyDepartment of General Practice and Family Medicine, University Bielefeld, Bielefeld, GermanyDepartment of General Practice and Family Medicine, University Bielefeld, Bielefeld, GermanyDepartment of Primary Care, University of Marburg, Marburg, GermanyIntroduction Atherosclerotic cardiovascular disease (ASCVD) was the main cause of death in Germany in 2021, with major risk factors (ie, hypertension, diabetes, dyslipidaemia, obesity and certain lifestyle factors) being highly prevalent. Preventing ASCVD by assessment and modification of these risk factors is an important challenge for general practitioners. This study aims to systematically review and synthesise recent recommendations of national and international guidelines regarding the primary prevention of ASCVD in adults in primary care.Methods and analysis We will conduct a systematic review of clinical practice guidelines (CPGs) to evaluate primary prevention strategies for ASCVD. CPGs will be retrieved from MEDLINE and the Turning Research Into Practice database, guideline-specific databases and websites of guidelines-producing societies, with searches limited to publications from 2016 onwards. We will include CPGs in English, Spanish, German or Dutch languages that provide evidence-based recommendations for ASCVD prevention. The study population will include adults without diagnosed ASCVD. Two independent reviewers will assess guideline eligibility and quality by means of the mini-checklist MiChe, and extract study characteristics and relevant recommendations for further consistency analysis. A third reviewer will resolve disagreements. Findings will be presented as a narrative synthesis and in tabular form.Ethics and dissemination This review does not require ethical approval. Our systematic review will inform the CPG of the German College of General Practitioners and Family Physicians on the primary prevention of ASCVD. The review results will also be disseminated through publications in peer-reviewed journals and presentations at local, national and international conferences.PROSPERO registration number CRD42023394605.https://bmjopen.bmj.com/content/13/12/e074788.full |
| spellingShingle | Veronika van der Wardt Christiane Muth Lara Schürmann Maren Bredehorst Ana I González-González Svetlana Puzhko Joerg Haasenritter Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: study protocol for a systematic guideline review BMJ Open |
| title | Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: study protocol for a systematic guideline review |
| title_full | Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: study protocol for a systematic guideline review |
| title_fullStr | Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: study protocol for a systematic guideline review |
| title_full_unstemmed | Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: study protocol for a systematic guideline review |
| title_short | Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: study protocol for a systematic guideline review |
| title_sort | recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care study protocol for a systematic guideline review |
| url | https://bmjopen.bmj.com/content/13/12/e074788.full |
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