Multigene profiling of single circulating tumor cells

Numerous techniques for isolating circulating tumor cells (CTCs) have been developed. Concurrently, single-cell techniques that can reveal molecular components of CTCs have become widely available. We discuss how the combination of isolation and multigene profiling of single CTCs in our platform can...

Full description

Bibliographic Details
Main Authors: Seung-min Park, Dawson J. Wong, Chin Chun Ooi, Jared C. Nesvet, Viswam S. Nair, Shan X. Wang, Sanjiv S. Gambhir
Format: Article
Language:English
Published: Taylor & Francis Group 2017-03-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2017.1289295
_version_ 1827809420820611072
author Seung-min Park
Dawson J. Wong
Chin Chun Ooi
Jared C. Nesvet
Viswam S. Nair
Shan X. Wang
Sanjiv S. Gambhir
author_facet Seung-min Park
Dawson J. Wong
Chin Chun Ooi
Jared C. Nesvet
Viswam S. Nair
Shan X. Wang
Sanjiv S. Gambhir
author_sort Seung-min Park
collection DOAJ
description Numerous techniques for isolating circulating tumor cells (CTCs) have been developed. Concurrently, single-cell techniques that can reveal molecular components of CTCs have become widely available. We discuss how the combination of isolation and multigene profiling of single CTCs in our platform can facilitate eventual translation to the clinic.
first_indexed 2024-03-11T22:40:46Z
format Article
id doaj.art-744a9e15af634fc88f26b0526849567c
institution Directory Open Access Journal
issn 2372-3556
language English
last_indexed 2024-03-11T22:40:46Z
publishDate 2017-03-01
publisher Taylor & Francis Group
record_format Article
series Molecular & Cellular Oncology
spelling doaj.art-744a9e15af634fc88f26b0526849567c2023-09-22T09:10:58ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562017-03-014210.1080/23723556.2017.12892951289295Multigene profiling of single circulating tumor cellsSeung-min Park0Dawson J. Wong1Chin Chun Ooi2Jared C. Nesvet3Viswam S. Nair4Shan X. Wang5Sanjiv S. Gambhir6Stanford University School of MedicineStanford UniversityStanford UniversityStanford UniversityStanford University School of MedicineStanford UniversityStanford University School of MedicineNumerous techniques for isolating circulating tumor cells (CTCs) have been developed. Concurrently, single-cell techniques that can reveal molecular components of CTCs have become widely available. We discuss how the combination of isolation and multigene profiling of single CTCs in our platform can facilitate eventual translation to the clinic.http://dx.doi.org/10.1080/23723556.2017.1289295circulating tumor cellsrare-cell sortingsingle-cell analysis
spellingShingle Seung-min Park
Dawson J. Wong
Chin Chun Ooi
Jared C. Nesvet
Viswam S. Nair
Shan X. Wang
Sanjiv S. Gambhir
Multigene profiling of single circulating tumor cells
Molecular & Cellular Oncology
circulating tumor cells
rare-cell sorting
single-cell analysis
title Multigene profiling of single circulating tumor cells
title_full Multigene profiling of single circulating tumor cells
title_fullStr Multigene profiling of single circulating tumor cells
title_full_unstemmed Multigene profiling of single circulating tumor cells
title_short Multigene profiling of single circulating tumor cells
title_sort multigene profiling of single circulating tumor cells
topic circulating tumor cells
rare-cell sorting
single-cell analysis
url http://dx.doi.org/10.1080/23723556.2017.1289295
work_keys_str_mv AT seungminpark multigeneprofilingofsinglecirculatingtumorcells
AT dawsonjwong multigeneprofilingofsinglecirculatingtumorcells
AT chinchunooi multigeneprofilingofsinglecirculatingtumorcells
AT jaredcnesvet multigeneprofilingofsinglecirculatingtumorcells
AT viswamsnair multigeneprofilingofsinglecirculatingtumorcells
AT shanxwang multigeneprofilingofsinglecirculatingtumorcells
AT sanjivsgambhir multigeneprofilingofsinglecirculatingtumorcells