The serotype distribution among healthy carriers before vaccination is essential for predicting the impact of pneumococcal conjugate vaccine on invasive disease.

Pneumococcal conjugate vaccines (PCVs) have substantially reduced morbidity and mortality of pneumococcal disease. The impact of the 7-valent PCV on all-serotype invasive pneumococcal disease (IPD) among children was reported to vary between high-income countries. We investigate the ability to predi...

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Detalles Bibliográficos
Autores principales: Stefan Flasche, Olivier Le Polain de Waroux, Katherine L O'Brien, W John Edmunds
Formato: Artículo
Lenguaje:English
Publicado: Public Library of Science (PLoS) 2015-04-01
Colección:PLoS Computational Biology
Acceso en línea:http://europepmc.org/articles/PMC4400047?pdf=render