Does fibroblast growth factor 23 correlates with volume status in hemodialysis patients?
Introduction: Volume overload is a known risk factor for cardiovascular disease and stroke in hemodialysis patients. The use of fibroblast growth factor 23 (FGF23) as a volume overload marker has been validated in multiple studies. Objectives: This is a prospective cross-sectional study considering...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2019-10-01
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| Series: | Journal of Nephropathology |
| Subjects: | |
| Online Access: | https://nephropathol.com/PDF/jnp-8-e35.pdf |
| _version_ | 1797827980283609088 |
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| author | Farzanehsadat Minoo Azam Alamdari Hamed Karimi |
| author_facet | Farzanehsadat Minoo Azam Alamdari Hamed Karimi |
| author_sort | Farzanehsadat Minoo |
| collection | DOAJ |
| description | Introduction: Volume overload is a known risk factor for cardiovascular disease and stroke in hemodialysis patients. The use of fibroblast growth factor 23 (FGF23) as a volume overload marker has been validated in multiple studies. Objectives: This is a prospective cross-sectional study considering the association between FGF23 and bioimpedance-measured volume overload in hemodialysis patients. Patients and Methods: Bioimpedance analysis was performed on 43 hemodialysis patients at the end of hemodialysis to evaluate the remaining volume overload and serum FGF23 was measured before hemodialysis. Results: The results indicated no significant correlation between mean serum FGF23 levels and volume overload in hemodialysis patients (P=0.824). Conclusion: Although this study did not show any association between volume overload and FGF23, further studies are needed to define the role of FGF23 as a volume overload marker. |
| first_indexed | 2024-04-09T12:57:07Z |
| format | Article |
| id | doaj.art-744b5917ceb0479ba97a59ce846d0eb6 |
| institution | Directory Open Access Journal |
| issn | 2251-8363 2251-8819 |
| language | English |
| last_indexed | 2024-04-09T12:57:07Z |
| publishDate | 2019-10-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropathology |
| spelling | doaj.art-744b5917ceb0479ba97a59ce846d0eb62023-05-13T11:27:47ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192019-10-0184e35e3510.15171/jnp.2019.35jnp-2759Does fibroblast growth factor 23 correlates with volume status in hemodialysis patients?Farzanehsadat Minoo0Azam Alamdari1Hamed Karimi2Nephrology Research Center, Tehran University of Medical Sciences, Tehran, IranNephrology Research Center, Tehran University of Medical Sciences, Tehran, IranNephrology Research Center, Tehran University of Medical Sciences, Tehran, IranIntroduction: Volume overload is a known risk factor for cardiovascular disease and stroke in hemodialysis patients. The use of fibroblast growth factor 23 (FGF23) as a volume overload marker has been validated in multiple studies. Objectives: This is a prospective cross-sectional study considering the association between FGF23 and bioimpedance-measured volume overload in hemodialysis patients. Patients and Methods: Bioimpedance analysis was performed on 43 hemodialysis patients at the end of hemodialysis to evaluate the remaining volume overload and serum FGF23 was measured before hemodialysis. Results: The results indicated no significant correlation between mean serum FGF23 levels and volume overload in hemodialysis patients (P=0.824). Conclusion: Although this study did not show any association between volume overload and FGF23, further studies are needed to define the role of FGF23 as a volume overload marker.https://nephropathol.com/PDF/jnp-8-e35.pdffibroblast growth factor 23hemodialysisvolume statusoverloadbio-impedance analysischronic kidney disease |
| spellingShingle | Farzanehsadat Minoo Azam Alamdari Hamed Karimi Does fibroblast growth factor 23 correlates with volume status in hemodialysis patients? Journal of Nephropathology fibroblast growth factor 23 hemodialysis volume status overload bio-impedance analysis chronic kidney disease |
| title | Does fibroblast growth factor 23 correlates with volume status in hemodialysis patients? |
| title_full | Does fibroblast growth factor 23 correlates with volume status in hemodialysis patients? |
| title_fullStr | Does fibroblast growth factor 23 correlates with volume status in hemodialysis patients? |
| title_full_unstemmed | Does fibroblast growth factor 23 correlates with volume status in hemodialysis patients? |
| title_short | Does fibroblast growth factor 23 correlates with volume status in hemodialysis patients? |
| title_sort | does fibroblast growth factor 23 correlates with volume status in hemodialysis patients |
| topic | fibroblast growth factor 23 hemodialysis volume status overload bio-impedance analysis chronic kidney disease |
| url | https://nephropathol.com/PDF/jnp-8-e35.pdf |
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