Biophysical analysis of apolipoprotein E3 variants linked with development of type III hyperlipoproteinemia.
Apolipoprotein E (apoE) is a major protein of the lipoprotein transport system that plays important roles in lipid homeostasis and protection from atherosclerosis. ApoE is characterized by structural plasticity and thermodynamic instability and can undergo significant structural rearrangements as pa...
Main Authors: | Dimitra Georgiadou, Angeliki Chroni, Alexander Vezeridis, Vassilis I Zannis, Efstratios Stratikos |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3206067?pdf=render |
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