Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development

Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development

Abstract Background Lysine-specific histone demethylase 5C (KDM5C) belongs to the jumonji family of demethylases and is specific for the di- and tri-demethylation of lysine 4 residues on histone 3 (H3K4 me2/3). KDM5C is expressed in the brain and skeletal muscles of humans and is associated with var...

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Main Authors: Youni Kim, Youngeun Jeong, Kujin Kwon, Tayaba Ismail, Hyun-Kyung Lee, Chowon Kim, Jeen-Woo Park, Oh-Shin Kwon, Beom-Sik Kang, Dong-Seok Lee, Tae Joo Park, Taejoon Kwon, Hyun-Shik Lee
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Epigenetics & Chromatin
Subjects:
Histone demethylase
Neural crest development
Eye formation
Embryogenesis
Organogenesis
Online Access:http://link.springer.com/article/10.1186/s13072-018-0241-x

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