Mouse model of colorectal cancer: Orthotopic co-implantation of tumor and stroma cells in cecum and rectum

Mouse model of colorectal cancer: Orthotopic co-implantation of tumor and stroma cells in cecum and rectum

Summary: In vivo interrogation of the functional role of genes implicated in colorectal cancer (CRC) is limited by the need for physiological models that mimic the disease. Here, we describe a protocol that provides the steps required for the orthotopic co-implantation of tumoral and stromal cells i...

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Bibliographic Details
Main Authors: Hiroaki Kasashima, Angeles Duran, Tania Cid-Diaz, Yu Muta, Hiroto Kinoshita, Eduard Batlle, Maria T. Diaz-Meco, Jorge Moscat
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:STAR Protocols
Subjects:
Cancer
Model organisms
Organoids
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721000046

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