Intratumoral Delivery of Interleukin 9 via Oncolytic Vaccinia Virus Elicits Potent Antitumor Effects in Tumor Models

Intratumoral Delivery of Interleukin 9 via Oncolytic Vaccinia Virus Elicits Potent Antitumor Effects in Tumor Models

The success of cancer immunotherapy is largely associated with immunologically hot tumors. Approaches that promote the infiltration of immune cells into tumor beds are urgently needed to transform cold tumors into hot tumors. Oncolytic viruses can transform the tumor microenvironment (TME), resultin...

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Bibliographic Details
Main Authors: Junjie Ye, Lingjuan Chen, Julia Waltermire, Jinshun Zhao, Jinghua Ren, Zongsheng Guo, David L. Bartlett, Zuqiang Liu
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
oncolytic virus
colon cancer
IL-9
IL-10
tumor microenvironment
modulation
Online Access:https://www.mdpi.com/2072-6694/16/5/1021

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