Promoter methylation of CDKN2A and lack of p16 expression characterize patients with hepatocellular carcinoma

Promoter methylation of CDKN2A and lack of p16 expression characterize patients with hepatocellular carcinoma

<p>Abstract</p> <p>Background</p> <p>The product of CDKN2A, p16 is an essential regulator of the cell cycle controlling the entry into the S-phase. Herein, we evaluated CDKN2A promoter methylation and p16 protein expression for the differentiation of hepatocellular carc...

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Bibliographic Details
Main Authors: Schneider-Stock Regine, Röcken Christoph, Ebert Matthias PA, Csepregi Antal, Hoffmann Juliane, Schulz Hans-Ulrich, Roessner Albert, Malfertheiner Peter
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/317

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