Kajian Praklinis Pemberian Oral Bubuk Keringbeku Susu Kedelai yang Difermentasi oleh Lactobacillus plantarum AP1 Dan Sphingobacterium sp. TB17 pada Tikus
To investigate the effects of oral administration of freeze-dried soymilks fermented by Lactobacillus plantarum AP1 andSphingobacterium sp. TB17, in preclinical study groups of male Sprague Dawley rats were fed for 3 weeks with four different test diets:basal diet (CD), basal diet supplemented with...
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| Format: | Article |
| Language: | English |
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Indonesian Biological Society
2012-05-01
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| Series: | Journal of Biological Researches |
| Subjects: | |
| Online Access: | http://berkalahayati.org/journal/86ea612d |
| _version_ | 1818381469472522240 |
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| author | Achmad Dinoto Rita Dwi Rahayu Sri Purwaningsih |
| author_facet | Achmad Dinoto Rita Dwi Rahayu Sri Purwaningsih |
| author_sort | Achmad Dinoto |
| collection | DOAJ |
| description | To investigate the effects of oral administration of freeze-dried soymilks fermented by Lactobacillus plantarum AP1 andSphingobacterium sp. TB17, in preclinical study groups of male Sprague Dawley rats were fed for 3 weeks with four different test diets:basal diet (CD), basal diet supplemented with 3% (w/w feed) freeze-dried unfermented soymilk (CN), basal diet supplemented with 3%(w/w feed) freeze-dried soymilk fermented by L. plantarum AP1 (CL), and basal diet supplemented with 3% (w/w feed) freeze-driedsoymilk fermented by Sphingobacterium sp. TB17 (CK). Our result showed a reduction of serum cholesterol level up to 15% in rats CBafter three weeks consuming soymilk fermented by L. plantarum AP1. This yield was relatively higher than that of rats CK consumingsoymilk fermented by Sphingobacterium sp. TB17 to reduce serum cholesterol only up to 5%. Although unfermented soymilk (CN)also showed the hypocholesterolomic effect to rats, the reduction of cholesterol serum level was lower than that of rat CL. There wereno signifi cant increased in blood glucose and body weight of rats as impact of freeze-dried fermented soymilk. Interestingly, althoughfeed intake tends to increase during fermented soymilk consumption, the body weight of rats did not increase. In general, this studyindicated that L. plantarum AP1 soymilk is a promising benefi cial food product for the health. |
| first_indexed | 2024-12-14T02:35:04Z |
| format | Article |
| id | doaj.art-74549df70f10409dbcfee42a27cf2720 |
| institution | Directory Open Access Journal |
| issn | 0852-6834 2337-389X |
| language | English |
| last_indexed | 2024-12-14T02:35:04Z |
| publishDate | 2012-05-01 |
| publisher | Indonesian Biological Society |
| record_format | Article |
| series | Journal of Biological Researches |
| spelling | doaj.art-74549df70f10409dbcfee42a27cf27202022-12-21T23:20:09ZengIndonesian Biological SocietyJournal of Biological Researches0852-68342337-389X2012-05-0116217317810.23869/bphjbr.16.2.201111Kajian Praklinis Pemberian Oral Bubuk Keringbeku Susu Kedelai yang Difermentasi oleh Lactobacillus plantarum AP1 Dan Sphingobacterium sp. TB17 pada TikusAchmad Dinoto0Rita Dwi Rahayu1Sri Purwaningsih2Pusat Penelitian Biologi, Lembaga Ilmu Pengetahuan Indonesia (LIPI) Jl Raya Jakarta-Bogor Km 46 Cibinong 16911 Indonesia. Telp. +62-21-8765066 Fax. +62-21-8765062Pusat Penelitian Biologi, Lembaga Ilmu Pengetahuan Indonesia (LIPI) Jl Raya Jakarta-Bogor Km 46 Cibinong 16911 Indonesia. Telp. +62-21-8765066 Fax. +62-21-8765062Pusat Penelitian Biologi, Lembaga Ilmu Pengetahuan Indonesia (LIPI) Jl Raya Jakarta-Bogor Km 46 Cibinong 16911 Indonesia. Telp. +62-21-8765066 Fax. +62-21-8765062To investigate the effects of oral administration of freeze-dried soymilks fermented by Lactobacillus plantarum AP1 andSphingobacterium sp. TB17, in preclinical study groups of male Sprague Dawley rats were fed for 3 weeks with four different test diets:basal diet (CD), basal diet supplemented with 3% (w/w feed) freeze-dried unfermented soymilk (CN), basal diet supplemented with 3%(w/w feed) freeze-dried soymilk fermented by L. plantarum AP1 (CL), and basal diet supplemented with 3% (w/w feed) freeze-driedsoymilk fermented by Sphingobacterium sp. TB17 (CK). Our result showed a reduction of serum cholesterol level up to 15% in rats CBafter three weeks consuming soymilk fermented by L. plantarum AP1. This yield was relatively higher than that of rats CK consumingsoymilk fermented by Sphingobacterium sp. TB17 to reduce serum cholesterol only up to 5%. Although unfermented soymilk (CN)also showed the hypocholesterolomic effect to rats, the reduction of cholesterol serum level was lower than that of rat CL. There wereno signifi cant increased in blood glucose and body weight of rats as impact of freeze-dried fermented soymilk. Interestingly, althoughfeed intake tends to increase during fermented soymilk consumption, the body weight of rats did not increase. In general, this studyindicated that L. plantarum AP1 soymilk is a promising benefi cial food product for the health.http://berkalahayati.org/journal/86ea612dfermented soymilkLactobacillus plantarumpre-clinical studySphingobacteriumCholesterolFermented SoymilkPre-clinical study |
| spellingShingle | Achmad Dinoto Rita Dwi Rahayu Sri Purwaningsih Kajian Praklinis Pemberian Oral Bubuk Keringbeku Susu Kedelai yang Difermentasi oleh Lactobacillus plantarum AP1 Dan Sphingobacterium sp. TB17 pada Tikus Journal of Biological Researches fermented soymilk Lactobacillus plantarum pre-clinical study Sphingobacterium Cholesterol Fermented Soymilk Pre-clinical study |
| title | Kajian Praklinis Pemberian Oral Bubuk Keringbeku Susu Kedelai yang Difermentasi oleh Lactobacillus plantarum AP1 Dan Sphingobacterium sp. TB17 pada Tikus |
| title_full | Kajian Praklinis Pemberian Oral Bubuk Keringbeku Susu Kedelai yang Difermentasi oleh Lactobacillus plantarum AP1 Dan Sphingobacterium sp. TB17 pada Tikus |
| title_fullStr | Kajian Praklinis Pemberian Oral Bubuk Keringbeku Susu Kedelai yang Difermentasi oleh Lactobacillus plantarum AP1 Dan Sphingobacterium sp. TB17 pada Tikus |
| title_full_unstemmed | Kajian Praklinis Pemberian Oral Bubuk Keringbeku Susu Kedelai yang Difermentasi oleh Lactobacillus plantarum AP1 Dan Sphingobacterium sp. TB17 pada Tikus |
| title_short | Kajian Praklinis Pemberian Oral Bubuk Keringbeku Susu Kedelai yang Difermentasi oleh Lactobacillus plantarum AP1 Dan Sphingobacterium sp. TB17 pada Tikus |
| title_sort | kajian praklinis pemberian oral bubuk keringbeku susu kedelai yang difermentasi oleh lactobacillus plantarum ap1 dan sphingobacterium sp tb17 pada tikus |
| topic | fermented soymilk Lactobacillus plantarum pre-clinical study Sphingobacterium Cholesterol Fermented Soymilk Pre-clinical study |
| url | http://berkalahayati.org/journal/86ea612d |
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