Carbon Nanotubes—Potent Carriers for Targeted Drug Delivery in Rheumatoid Arthritis

Carbon Nanotubes—Potent Carriers for Targeted Drug Delivery in Rheumatoid Arthritis

Two types of single-walled carbon nanotubes (SWCNTs), HiPco- and carboxyl-SWCNT, are evaluated as drug carriers for the traditional anti-inflammatory drug methotrexate (MTX) and a small interfering RNA (siRNA) targeting NOTCH1 gene. The nanotubes are solubilized by PEGylation and covalently loaded w...

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Bibliographic Details
Main Authors: Camilla Kofoed Andersen, Sangita Khatri, Jonas Hansen, Sofie Slott, Rohith Pavan Parvathaneni, Ana C. Mendes, Ioannis S. Chronakis, Shu-Chen Hung, Narendiran Rajasekaran, Zhuoran Ma, Shoujun Zhu, Hongjie Dai, Elizabeth D. Mellins, Kira Astakhova
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmaceutics
Subjects:
carbon nanotubes
rheumatoid arthritis
siRNA
Online Access:https://www.mdpi.com/1999-4923/13/4/453

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