STalign: Alignment of spatial transcriptomics data using diffeomorphic metric mapping

STalign: Alignment of spatial transcriptomics data using diffeomorphic metric mapping

Abstract Spatial transcriptomics (ST) technologies enable high throughput gene expression characterization within thin tissue sections. However, comparing spatial observations across sections, samples, and technologies remains challenging. To address this challenge, we develop STalign to align ST da...

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Bibliographic Details
Main Authors: Kalen Clifton, Manjari Anant, Gohta Aihara, Lyla Atta, Osagie K. Aimiuwu, Justus M. Kebschull, Michael I. Miller, Daniel Tward, Jean Fan
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43915-7

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