The natural polyphenol curcumin induces apoptosis by suppressing STAT3 signaling in esophageal squamous cell carcinoma

The natural polyphenol curcumin induces apoptosis by suppressing STAT3 signaling in esophageal squamous cell carcinoma

Abstract Background We and others have previously shown that the STAT3 signaling pathway is activated in some esophageal squamous cell carcinoma (ESCC) cells and is required for the survival and growth of these primary ESCC-derived xenografts. It has also been shown that the natural polyphenol curcu...

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Bibliographic Details
Main Authors: Ying Liu, Xinhua Wang, Shuang Zeng, Xiane Zhang, Jimin Zhao, Xiaoyan Zhang, Xinhuan Chen, Wanjing Yang, Yili Yang, Ziming Dong, Jingyu Zhu, Xin Xu, Fang Tian
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Curcumin
STAT3
Esophageal squamous cell carcinoma
Apoptosis
PDX model
Online Access:http://link.springer.com/article/10.1186/s13046-018-0959-0

Internet

http://link.springer.com/article/10.1186/s13046-018-0959-0

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