Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan

β-Carbolines are an alkaloid containing indole group that easily passes through the blood-brain barrier and change the concentration of neurotransmitters, as well as a range of neurophysiological and toxic effects, including effects on body temperature, seizures, anti-depressant activity, vascular d...

Full description

Bibliographic Details
Main Authors: Saeedeh Fahimi, Shahrbanoo Oryan, Ramesh Ahmadi, Akram Eidi
Format: Article
Language:fas
Published: Qom Islamic Azad University 2019-10-01
Series:بیولوژی کاربردی
Subjects:
Online Access:https://sjoapb.qom.iau.ir/article_672419_bc877c49c99fc5245e7b7aea93393a00.pdf
_version_ 1797778178555510784
author Saeedeh Fahimi
Shahrbanoo Oryan
Ramesh Ahmadi
Akram Eidi
author_facet Saeedeh Fahimi
Shahrbanoo Oryan
Ramesh Ahmadi
Akram Eidi
author_sort Saeedeh Fahimi
collection DOAJ
description β-Carbolines are an alkaloid containing indole group that easily passes through the blood-brain barrier and change the concentration of neurotransmitters, as well as a range of neurophysiological and toxic effects, including effects on body temperature, seizures, anti-depressant activity, vascular dilatation, anti-cumulative effects of platelets and effects on appetite. The aim of this study was to extract and measure β-Carboline and also phenolic compounds of Spand (p.harmala) collected from Zahedan. Further phytochemical analysis of extracts was carried out and the quantitative and qualitative analysis included identification of anthocyanins, flavonoids, tannins, anthraquinones, an antioxidant test of extract, FT-IR analysis of extract, quantitative and qualitative analysis of HPLC extract and alkaloids. The results showed that although the antioxidant properties of methanolic extract from leaves are higher (due to the presence of flavonoids and phenolic compounds) than the methanolic extract seeds, the amount of β-Carboline in the seeds of this plant (p.harmala) is higher.
first_indexed 2024-03-12T23:13:32Z
format Article
id doaj.art-7463b178e1ac46529c126650eaa70092
institution Directory Open Access Journal
issn 2538-3434
language fas
last_indexed 2024-03-12T23:13:32Z
publishDate 2019-10-01
publisher Qom Islamic Azad University
record_format Article
series بیولوژی کاربردی
spelling doaj.art-7463b178e1ac46529c126650eaa700922023-07-17T14:57:33ZfasQom Islamic Azad Universityبیولوژی کاربردی2538-34342019-10-01935115672419Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of ZahedanSaeedeh Fahimi0Shahrbanoo Oryan1Ramesh Ahmadi2Akram Eidi3Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran1. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran 2. Department of Animal Sciences, Faculty of Biological Sciences, Kharazmi University, Tehran, IranDepartment of Animal Sciences, Faculty of Basic Sciences, Islamic Azad University of Qom, Qom, IranDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iranβ-Carbolines are an alkaloid containing indole group that easily passes through the blood-brain barrier and change the concentration of neurotransmitters, as well as a range of neurophysiological and toxic effects, including effects on body temperature, seizures, anti-depressant activity, vascular dilatation, anti-cumulative effects of platelets and effects on appetite. The aim of this study was to extract and measure β-Carboline and also phenolic compounds of Spand (p.harmala) collected from Zahedan. Further phytochemical analysis of extracts was carried out and the quantitative and qualitative analysis included identification of anthocyanins, flavonoids, tannins, anthraquinones, an antioxidant test of extract, FT-IR analysis of extract, quantitative and qualitative analysis of HPLC extract and alkaloids. The results showed that although the antioxidant properties of methanolic extract from leaves are higher (due to the presence of flavonoids and phenolic compounds) than the methanolic extract seeds, the amount of β-Carboline in the seeds of this plant (p.harmala) is higher.https://sjoapb.qom.iau.ir/article_672419_bc877c49c99fc5245e7b7aea93393a00.pdfspand (p.harmala)β-carbolinephenolic compoundshigh performance liquid chromatography (hplc)
spellingShingle Saeedeh Fahimi
Shahrbanoo Oryan
Ramesh Ahmadi
Akram Eidi
Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan
بیولوژی کاربردی
spand (p.harmala)
β-carboline
phenolic compounds
high performance liquid chromatography (hplc)
title Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan
title_full Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan
title_fullStr Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan
title_full_unstemmed Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan
title_short Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan
title_sort extraction and measurement of β carbolines and evaluation of antioxidant properties of leaf and seed extract of spand p harmala of zahedan
topic spand (p.harmala)
β-carboline
phenolic compounds
high performance liquid chromatography (hplc)
url https://sjoapb.qom.iau.ir/article_672419_bc877c49c99fc5245e7b7aea93393a00.pdf
work_keys_str_mv AT saeedehfahimi extractionandmeasurementofbcarbolinesandevaluationofantioxidantpropertiesofleafandseedextractofspandpharmalaofzahedan
AT shahrbanoooryan extractionandmeasurementofbcarbolinesandevaluationofantioxidantpropertiesofleafandseedextractofspandpharmalaofzahedan
AT rameshahmadi extractionandmeasurementofbcarbolinesandevaluationofantioxidantpropertiesofleafandseedextractofspandpharmalaofzahedan
AT akrameidi extractionandmeasurementofbcarbolinesandevaluationofantioxidantpropertiesofleafandseedextractofspandpharmalaofzahedan