Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan
β-Carbolines are an alkaloid containing indole group that easily passes through the blood-brain barrier and change the concentration of neurotransmitters, as well as a range of neurophysiological and toxic effects, including effects on body temperature, seizures, anti-depressant activity, vascular d...
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Format: | Article |
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Qom Islamic Azad University
2019-10-01
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Series: | بیولوژی کاربردی |
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Online Access: | https://sjoapb.qom.iau.ir/article_672419_bc877c49c99fc5245e7b7aea93393a00.pdf |
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author | Saeedeh Fahimi Shahrbanoo Oryan Ramesh Ahmadi Akram Eidi |
author_facet | Saeedeh Fahimi Shahrbanoo Oryan Ramesh Ahmadi Akram Eidi |
author_sort | Saeedeh Fahimi |
collection | DOAJ |
description | β-Carbolines are an alkaloid containing indole group that easily passes through the blood-brain barrier and change the concentration of neurotransmitters, as well as a range of neurophysiological and toxic effects, including effects on body temperature, seizures, anti-depressant activity, vascular dilatation, anti-cumulative effects of platelets and effects on appetite. The aim of this study was to extract and measure β-Carboline and also phenolic compounds of Spand (p.harmala) collected from Zahedan. Further phytochemical analysis of extracts was carried out and the quantitative and qualitative analysis included identification of anthocyanins, flavonoids, tannins, anthraquinones, an antioxidant test of extract, FT-IR analysis of extract, quantitative and qualitative analysis of HPLC extract and alkaloids. The results showed that although the antioxidant properties of methanolic extract from leaves are higher (due to the presence of flavonoids and phenolic compounds) than the methanolic extract seeds, the amount of β-Carboline in the seeds of this plant (p.harmala) is higher. |
first_indexed | 2024-03-12T23:13:32Z |
format | Article |
id | doaj.art-7463b178e1ac46529c126650eaa70092 |
institution | Directory Open Access Journal |
issn | 2538-3434 |
language | fas |
last_indexed | 2024-03-12T23:13:32Z |
publishDate | 2019-10-01 |
publisher | Qom Islamic Azad University |
record_format | Article |
series | بیولوژی کاربردی |
spelling | doaj.art-7463b178e1ac46529c126650eaa700922023-07-17T14:57:33ZfasQom Islamic Azad Universityبیولوژی کاربردی2538-34342019-10-01935115672419Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of ZahedanSaeedeh Fahimi0Shahrbanoo Oryan1Ramesh Ahmadi2Akram Eidi3Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran1. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran 2. Department of Animal Sciences, Faculty of Biological Sciences, Kharazmi University, Tehran, IranDepartment of Animal Sciences, Faculty of Basic Sciences, Islamic Azad University of Qom, Qom, IranDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iranβ-Carbolines are an alkaloid containing indole group that easily passes through the blood-brain barrier and change the concentration of neurotransmitters, as well as a range of neurophysiological and toxic effects, including effects on body temperature, seizures, anti-depressant activity, vascular dilatation, anti-cumulative effects of platelets and effects on appetite. The aim of this study was to extract and measure β-Carboline and also phenolic compounds of Spand (p.harmala) collected from Zahedan. Further phytochemical analysis of extracts was carried out and the quantitative and qualitative analysis included identification of anthocyanins, flavonoids, tannins, anthraquinones, an antioxidant test of extract, FT-IR analysis of extract, quantitative and qualitative analysis of HPLC extract and alkaloids. The results showed that although the antioxidant properties of methanolic extract from leaves are higher (due to the presence of flavonoids and phenolic compounds) than the methanolic extract seeds, the amount of β-Carboline in the seeds of this plant (p.harmala) is higher.https://sjoapb.qom.iau.ir/article_672419_bc877c49c99fc5245e7b7aea93393a00.pdfspand (p.harmala)β-carbolinephenolic compoundshigh performance liquid chromatography (hplc) |
spellingShingle | Saeedeh Fahimi Shahrbanoo Oryan Ramesh Ahmadi Akram Eidi Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan بیولوژی کاربردی spand (p.harmala) β-carboline phenolic compounds high performance liquid chromatography (hplc) |
title | Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan |
title_full | Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan |
title_fullStr | Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan |
title_full_unstemmed | Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan |
title_short | Extraction and measurement of β-Carbolines and evaluation of antioxidant properties of leaf and seed extract of Spand (P.harmala) of Zahedan |
title_sort | extraction and measurement of β carbolines and evaluation of antioxidant properties of leaf and seed extract of spand p harmala of zahedan |
topic | spand (p.harmala) β-carboline phenolic compounds high performance liquid chromatography (hplc) |
url | https://sjoapb.qom.iau.ir/article_672419_bc877c49c99fc5245e7b7aea93393a00.pdf |
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