An iterative method for robust in-line phase contrast imaging

We present an iterative near-field in-line phase contrast method that allows quantitative determination of the thickness of an object given the refractive index of the sample material. The iterative method allows for quantitative phase contrast imaging in regimes where the contrast transfer function...

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Main Authors: Aidan J Carroll, Grant A van Riessen, Eugeniu Balaur, Igor P Dolbnya, Giang N Tran, Andrew G Peele
Format: Article
Language:English
Published: IOP Publishing 2016-01-01
Series:New Journal of Physics
Subjects:
Online Access:https://doi.org/10.1088/1367-2630/18/4/043003
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author Aidan J Carroll
Grant A van Riessen
Eugeniu Balaur
Igor P Dolbnya
Giang N Tran
Andrew G Peele
author_facet Aidan J Carroll
Grant A van Riessen
Eugeniu Balaur
Igor P Dolbnya
Giang N Tran
Andrew G Peele
author_sort Aidan J Carroll
collection DOAJ
description We present an iterative near-field in-line phase contrast method that allows quantitative determination of the thickness of an object given the refractive index of the sample material. The iterative method allows for quantitative phase contrast imaging in regimes where the contrast transfer function (CTF) and transport of intensity equation (TIE) cannot be applied. Further, the nature of the iterative scheme offers more flexibility and potentially allows more high-resolution image reconstructions when compared to TIE method and less artefacts when compared to the CTF method. While, not addressed here, extension of our approach in future work to broadband illumination will also be straightforward as the wavelength dependence of the refractive index of an object can be readily incorporated into the iterative approach.
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spelling doaj.art-7464039f54974971872e8419b4cc7ff92023-08-08T14:29:50ZengIOP PublishingNew Journal of Physics1367-26302016-01-0118404300310.1088/1367-2630/18/4/043003An iterative method for robust in-line phase contrast imagingAidan J Carroll0Grant A van Riessen1Eugeniu Balaur2Igor P Dolbnya3Giang N Tran4Andrew G Peele5Department of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Victoria 3086, AustraliaDepartment of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Victoria 3086, Australia; ARC Centre of Excellence for Advanced Molecular ImagingDepartment of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Victoria 3086, Australia; ARC Centre of Excellence for Advanced Molecular ImagingDiamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 ODE, EnglandDepartment of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Victoria 3086, AustraliaDepartment of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Victoria 3086, Australia; ARC Centre of Excellence for Advanced Molecular Imaging; Australian Synchrotron, 800 Blackburn Rd, Clayton, Victoria 3168, AustraliaWe present an iterative near-field in-line phase contrast method that allows quantitative determination of the thickness of an object given the refractive index of the sample material. The iterative method allows for quantitative phase contrast imaging in regimes where the contrast transfer function (CTF) and transport of intensity equation (TIE) cannot be applied. Further, the nature of the iterative scheme offers more flexibility and potentially allows more high-resolution image reconstructions when compared to TIE method and less artefacts when compared to the CTF method. While, not addressed here, extension of our approach in future work to broadband illumination will also be straightforward as the wavelength dependence of the refractive index of an object can be readily incorporated into the iterative approach.https://doi.org/10.1088/1367-2630/18/4/043003x-ray microscopeiterative algorithmnear fieldphase contrast imaging
spellingShingle Aidan J Carroll
Grant A van Riessen
Eugeniu Balaur
Igor P Dolbnya
Giang N Tran
Andrew G Peele
An iterative method for robust in-line phase contrast imaging
New Journal of Physics
x-ray microscope
iterative algorithm
near field
phase contrast imaging
title An iterative method for robust in-line phase contrast imaging
title_full An iterative method for robust in-line phase contrast imaging
title_fullStr An iterative method for robust in-line phase contrast imaging
title_full_unstemmed An iterative method for robust in-line phase contrast imaging
title_short An iterative method for robust in-line phase contrast imaging
title_sort iterative method for robust in line phase contrast imaging
topic x-ray microscope
iterative algorithm
near field
phase contrast imaging
url https://doi.org/10.1088/1367-2630/18/4/043003
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