Kisspeptin treatment reverses high prolactin levels and improves gonadal function in hypothyroid male rats

Kisspeptin treatment reverses high prolactin levels and improves gonadal function in hypothyroid male rats

Abstract We evaluated whether the administration of kisspeptin-10 (Kp10) is capable of restoring gonadal function in hypothyroid male rats. Hypothyroidism was induced with 6-propyl-2-thiouracil (PTU) for three months. In the last month, half of the hypothyroid animals were treated with Kp10. Hypothy...

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Main Authors: Luciano Cardoso Santos, Jeane Martinha dos Anjos Cordeiro, Larissa da Silva Santana, Erikles Macêdo Barbosa, Bianca Reis Santos, Letícia Dias Mendonça, Maria Clara da Silva Galrão Cunha, William Morais Machado, Larissa Rodrigues Santana, Maíra Guimarães Kersul, Patrícia Costa Henriques, Roberta Araújo Lopes, Paola Pereira das Neves Snoeck, Raphael Escorsim Szawka, Juneo Freitas Silva
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-44056-z

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