EEG UPPER/LOW ALPHA FREQUENCY POWER RATIO RELATES TO TEMPORO-PARIETAL BRAIN ATROPHY AND MEMORY PERFORMANCES IN MILD COGNITIVE IMPAIRMENT
Objective: temporo-parietal cortex thinning is associated to mild cognitive impairment (MCI) due to Alzheimer disease (AD). The increase of EEG upper/low alpha power ratio has been associated with AD-converter MCI subjects. We investigated the association of alpha3/alpha2 ratio with patterns of cort...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-10-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00063/full |
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| author | Davide Vito Moretti donata epaternicò Giuliano eBinetti Orazio eZanetti giovanni b Frisoni |
| author_facet | Davide Vito Moretti donata epaternicò Giuliano eBinetti Orazio eZanetti giovanni b Frisoni |
| author_sort | Davide Vito Moretti |
| collection | DOAJ |
| description | Objective: temporo-parietal cortex thinning is associated to mild cognitive impairment (MCI) due to Alzheimer disease (AD). The increase of EEG upper/low alpha power ratio has been associated with AD-converter MCI subjects. We investigated the association of alpha3/alpha2 ratio with patterns of cortical thickness in MCI.Methods: 74 adult subjects with MCI underwent clinical and neuropsychological evaluation, electroencephalogram (EEG) recording and high resolution 3D magnetic resonance imaging (MRI). Alpha3/alpha2 power ratio as well as cortical thickness was computed for each subject. Three MCI groups were detected according to increasing tertile values of upper/low alpha power ratio . Difference of cortical thikness among the groups was estimated. Pearson’s r was used to assess the topography of the correlation between cortical thinning and memory impairment.Results: High upper/low alpha power ratio group had total cortical grey matter (CGM) volume reduction of 471 mm2 than low upper/low alpha power ratio group (p |
| first_indexed | 2024-12-11T04:43:11Z |
| format | Article |
| id | doaj.art-746b413c5bbf479c9ebe32497be46cc9 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-12-11T04:43:11Z |
| publishDate | 2013-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-746b413c5bbf479c9ebe32497be46cc92022-12-22T01:20:34ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652013-10-01510.3389/fnagi.2013.0006365285EEG UPPER/LOW ALPHA FREQUENCY POWER RATIO RELATES TO TEMPORO-PARIETAL BRAIN ATROPHY AND MEMORY PERFORMANCES IN MILD COGNITIVE IMPAIRMENTDavide Vito Moretti0donata epaternicò1Giuliano eBinetti2Orazio eZanetti3giovanni b Frisoni4National Insitute for Research and Cure of mental disorders and Alzheimer's disease-FatebenefratelliNational Insitute for Research and Cure of mental disorders and Alzheimer's disease-FatebenefratelliNational Insitute for Research and Cure of mental disorders and Alzheimer's disease-FatebenefratelliNational Insitute for Research and Cure of mental disorders and Alzheimer's disease-FatebenefratelliNational Insitute for Research and Cure of mental disorders and Alzheimer's disease-FatebenefratelliObjective: temporo-parietal cortex thinning is associated to mild cognitive impairment (MCI) due to Alzheimer disease (AD). The increase of EEG upper/low alpha power ratio has been associated with AD-converter MCI subjects. We investigated the association of alpha3/alpha2 ratio with patterns of cortical thickness in MCI.Methods: 74 adult subjects with MCI underwent clinical and neuropsychological evaluation, electroencephalogram (EEG) recording and high resolution 3D magnetic resonance imaging (MRI). Alpha3/alpha2 power ratio as well as cortical thickness was computed for each subject. Three MCI groups were detected according to increasing tertile values of upper/low alpha power ratio . Difference of cortical thikness among the groups was estimated. Pearson’s r was used to assess the topography of the correlation between cortical thinning and memory impairment.Results: High upper/low alpha power ratio group had total cortical grey matter (CGM) volume reduction of 471 mm2 than low upper/low alpha power ratio group (phttp://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00063/fullEEGMRIMCI-diagnosiscortical atrophyBRAIN RHTYHMS |
| spellingShingle | Davide Vito Moretti donata epaternicò Giuliano eBinetti Orazio eZanetti giovanni b Frisoni EEG UPPER/LOW ALPHA FREQUENCY POWER RATIO RELATES TO TEMPORO-PARIETAL BRAIN ATROPHY AND MEMORY PERFORMANCES IN MILD COGNITIVE IMPAIRMENT Frontiers in Aging Neuroscience EEG MRI MCI-diagnosis cortical atrophy BRAIN RHTYHMS |
| title | EEG UPPER/LOW ALPHA FREQUENCY POWER RATIO RELATES TO TEMPORO-PARIETAL BRAIN ATROPHY AND MEMORY PERFORMANCES IN MILD COGNITIVE IMPAIRMENT |
| title_full | EEG UPPER/LOW ALPHA FREQUENCY POWER RATIO RELATES TO TEMPORO-PARIETAL BRAIN ATROPHY AND MEMORY PERFORMANCES IN MILD COGNITIVE IMPAIRMENT |
| title_fullStr | EEG UPPER/LOW ALPHA FREQUENCY POWER RATIO RELATES TO TEMPORO-PARIETAL BRAIN ATROPHY AND MEMORY PERFORMANCES IN MILD COGNITIVE IMPAIRMENT |
| title_full_unstemmed | EEG UPPER/LOW ALPHA FREQUENCY POWER RATIO RELATES TO TEMPORO-PARIETAL BRAIN ATROPHY AND MEMORY PERFORMANCES IN MILD COGNITIVE IMPAIRMENT |
| title_short | EEG UPPER/LOW ALPHA FREQUENCY POWER RATIO RELATES TO TEMPORO-PARIETAL BRAIN ATROPHY AND MEMORY PERFORMANCES IN MILD COGNITIVE IMPAIRMENT |
| title_sort | eeg upper low alpha frequency power ratio relates to temporo parietal brain atrophy and memory performances in mild cognitive impairment |
| topic | EEG MRI MCI-diagnosis cortical atrophy BRAIN RHTYHMS |
| url | http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00063/full |
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