Biosimilars: New guns for the treatment of rheumatological patients?

The advent of biological therapies in 2000s has represented a real revolution in the treatment of patients affected by rheumatic diseases, but biosimilars represent nowadays a further revolution both from an economic point of view and for the accessibility to treatment for rheumatic patients. The ma...

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Main Authors: Daniela Marotto, Angela Ceribelli, Piercarlo Sarzi Puttini
Format: Article
Language:English
Published: Verduci Editore 2019-05-01
Series:Beyond Rheumatology
Subjects:
Online Access:https://www.beyond-rheumatology.org/wp-content/uploads/sites/10/2022/05/br-1-1-3.pdf
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author Daniela Marotto
Angela Ceribelli
Piercarlo Sarzi Puttini
author_facet Daniela Marotto
Angela Ceribelli
Piercarlo Sarzi Puttini
author_sort Daniela Marotto
collection DOAJ
description The advent of biological therapies in 2000s has represented a real revolution in the treatment of patients affected by rheumatic diseases, but biosimilars represent nowadays a further revolution both from an economic point of view and for the accessibility to treatment for rheumatic patients. The main scientific rheumatological societies have clearly expressed themselves on the biosimilars topic, by highlighting how they represent a great opportunity to contain costs and treat more patients, and these advantages should be accepted by rheumatologists. The use of biosimilars in different European countries varies widely; in fact, in some of them their use is mandatory (at least in naïve patients), while in other countries it is only recommended. The knowledge and consequently the acceptance of biosimilars are different among patients, and this also depends on the correct medical information on this topic. As more and more biosimilars receive regulatory approval and reach the market, it is essential for healthcare professionals to have the right knowledge about them, so that they are properly transferred to their patients. Biosimilars are not identical to the reference product, and clinicians are particularly interested in the safety and effectiveness of switching from the biooriginator to the bio-similar in experienced patients. We will develop these aspects on biosimilars in the present manuscript, for an update on current guidelines in their use in rheumatic patients.
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spelling doaj.art-746d883360734e8fb7805407eb447bd32023-05-08T14:41:23ZengVerduci EditoreBeyond Rheumatology2612-51102019-05-01110.4081/br.2019.3255Biosimilars: New guns for the treatment of rheumatological patients?Daniela Marotto0Angela Ceribelli1Piercarlo Sarzi Puttini2P. Dettori Hospital, Tempio Pausania (SS), ASST Fatebenefratelli-Sacco, Milan, University of Milan, Italy, The advent of biological therapies in 2000s has represented a real revolution in the treatment of patients affected by rheumatic diseases, but biosimilars represent nowadays a further revolution both from an economic point of view and for the accessibility to treatment for rheumatic patients. The main scientific rheumatological societies have clearly expressed themselves on the biosimilars topic, by highlighting how they represent a great opportunity to contain costs and treat more patients, and these advantages should be accepted by rheumatologists. The use of biosimilars in different European countries varies widely; in fact, in some of them their use is mandatory (at least in naïve patients), while in other countries it is only recommended. The knowledge and consequently the acceptance of biosimilars are different among patients, and this also depends on the correct medical information on this topic. As more and more biosimilars receive regulatory approval and reach the market, it is essential for healthcare professionals to have the right knowledge about them, so that they are properly transferred to their patients. Biosimilars are not identical to the reference product, and clinicians are particularly interested in the safety and effectiveness of switching from the biooriginator to the bio-similar in experienced patients. We will develop these aspects on biosimilars in the present manuscript, for an update on current guidelines in their use in rheumatic patients.https://www.beyond-rheumatology.org/wp-content/uploads/sites/10/2022/05/br-1-1-3.pdfbiological therapiesbiosimilarsswitchswapinterchangeabilityguidelinesrecommendations
spellingShingle Daniela Marotto
Angela Ceribelli
Piercarlo Sarzi Puttini
Biosimilars: New guns for the treatment of rheumatological patients?
Beyond Rheumatology
biological therapies
biosimilars
switch
swap
interchangeability
guidelines
recommendations
title Biosimilars: New guns for the treatment of rheumatological patients?
title_full Biosimilars: New guns for the treatment of rheumatological patients?
title_fullStr Biosimilars: New guns for the treatment of rheumatological patients?
title_full_unstemmed Biosimilars: New guns for the treatment of rheumatological patients?
title_short Biosimilars: New guns for the treatment of rheumatological patients?
title_sort biosimilars new guns for the treatment of rheumatological patients
topic biological therapies
biosimilars
switch
swap
interchangeability
guidelines
recommendations
url https://www.beyond-rheumatology.org/wp-content/uploads/sites/10/2022/05/br-1-1-3.pdf
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AT angelaceribelli biosimilarsnewgunsforthetreatmentofrheumatologicalpatients
AT piercarlosarziputtini biosimilarsnewgunsforthetreatmentofrheumatologicalpatients