Obstructive Sleep Apnea: Another Condition to Screen for in Women with Infertility
Women with obstructive sleep apnea (OSA) are at increased risk of poor pregnancy outcomes such as fetal growth restriction, hypertensive disorders of pregnancy, and gestational diabetes mellitus. Given this increased risk, we aimed to study the screening prevalence of OSA in women seeking fertility...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Women |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-4184/2/1/6 |
| _version_ | 1797440680025391104 |
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| author | Leeann M. Bui Mihaela Bazalakova Kathleen M. Antony Laura G. Cooney |
| author_facet | Leeann M. Bui Mihaela Bazalakova Kathleen M. Antony Laura G. Cooney |
| author_sort | Leeann M. Bui |
| collection | DOAJ |
| description | Women with obstructive sleep apnea (OSA) are at increased risk of poor pregnancy outcomes such as fetal growth restriction, hypertensive disorders of pregnancy, and gestational diabetes mellitus. Given this increased risk, we aimed to study the screening prevalence of OSA in women seeking fertility treatment. We performed a cross sectional study of patients presenting to a university-affiliated fertility clinic between March-April 2021. Patients were asked to complete OSA screening (STOP-BANG), anxiety screening (GAD-7), and depression screening (PHQ-2) questionnaires. 107 women completed the surveys. Mean age was 35.1 years and mean body mass index (BMI) was 25.7 kg/m<sup>2</sup>. Nine (8.4%) women screened positive for OSA using the STOP-BANG screening tool. Women who screened positive for OSA were more likely to be older (37.8 years vs. 34.7 years, <i>p</i> = 0.02) and have a higher BMI (42.6 kg/m<sup>2</sup> vs. 27.4 kg/m<sup>2</sup>, <i>p</i> < 0.001). Women who screened positive for OSA were also more likely to screen positive for mild-severe depressive symptoms (22.2% vs. 3.1%, <i>p</i> = 0.006) and mild-severe anxiety (66.7% vs. 21.4%, <i>p</i> = 0.003) symptoms. 24.3% of the population had polycystic ovary syndrome (PCOS). Women with PCOS were more likely to screen positive for OSA (19.2% vs. 4.9%; <i>p</i> = 0.04). Despite this being a low-risk population of young women seeking fertility evaluation or treatment, 8% screened positive for OSA. Given the association between OSA and adverse pregnancy outcomes, our results underline the need to screen women seeking fertility treatment. |
| first_indexed | 2024-03-09T12:12:53Z |
| format | Article |
| id | doaj.art-746ed4214cb14748a9c81d7f605a48ac |
| institution | Directory Open Access Journal |
| issn | 2673-4184 |
| language | English |
| last_indexed | 2024-03-09T12:12:53Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Women |
| spelling | doaj.art-746ed4214cb14748a9c81d7f605a48ac2023-11-30T22:50:31ZengMDPI AGWomen2673-41842022-02-0121566310.3390/women2010006Obstructive Sleep Apnea: Another Condition to Screen for in Women with InfertilityLeeann M. Bui0Mihaela Bazalakova1Kathleen M. Antony2Laura G. Cooney3Department of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53562, USADepartment of Neurology, Wisconsin Sleep, University of Wisconsin School of Medicine and Public Health, Madison, WI 53562, USADepartment of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53562, USADepartment of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53562, USAWomen with obstructive sleep apnea (OSA) are at increased risk of poor pregnancy outcomes such as fetal growth restriction, hypertensive disorders of pregnancy, and gestational diabetes mellitus. Given this increased risk, we aimed to study the screening prevalence of OSA in women seeking fertility treatment. We performed a cross sectional study of patients presenting to a university-affiliated fertility clinic between March-April 2021. Patients were asked to complete OSA screening (STOP-BANG), anxiety screening (GAD-7), and depression screening (PHQ-2) questionnaires. 107 women completed the surveys. Mean age was 35.1 years and mean body mass index (BMI) was 25.7 kg/m<sup>2</sup>. Nine (8.4%) women screened positive for OSA using the STOP-BANG screening tool. Women who screened positive for OSA were more likely to be older (37.8 years vs. 34.7 years, <i>p</i> = 0.02) and have a higher BMI (42.6 kg/m<sup>2</sup> vs. 27.4 kg/m<sup>2</sup>, <i>p</i> < 0.001). Women who screened positive for OSA were also more likely to screen positive for mild-severe depressive symptoms (22.2% vs. 3.1%, <i>p</i> = 0.006) and mild-severe anxiety (66.7% vs. 21.4%, <i>p</i> = 0.003) symptoms. 24.3% of the population had polycystic ovary syndrome (PCOS). Women with PCOS were more likely to screen positive for OSA (19.2% vs. 4.9%; <i>p</i> = 0.04). Despite this being a low-risk population of young women seeking fertility evaluation or treatment, 8% screened positive for OSA. Given the association between OSA and adverse pregnancy outcomes, our results underline the need to screen women seeking fertility treatment.https://www.mdpi.com/2673-4184/2/1/6obstructive sleep apneasleep disturbanceinfertilityfertilitypregnancydepression |
| spellingShingle | Leeann M. Bui Mihaela Bazalakova Kathleen M. Antony Laura G. Cooney Obstructive Sleep Apnea: Another Condition to Screen for in Women with Infertility Women obstructive sleep apnea sleep disturbance infertility fertility pregnancy depression |
| title | Obstructive Sleep Apnea: Another Condition to Screen for in Women with Infertility |
| title_full | Obstructive Sleep Apnea: Another Condition to Screen for in Women with Infertility |
| title_fullStr | Obstructive Sleep Apnea: Another Condition to Screen for in Women with Infertility |
| title_full_unstemmed | Obstructive Sleep Apnea: Another Condition to Screen for in Women with Infertility |
| title_short | Obstructive Sleep Apnea: Another Condition to Screen for in Women with Infertility |
| title_sort | obstructive sleep apnea another condition to screen for in women with infertility |
| topic | obstructive sleep apnea sleep disturbance infertility fertility pregnancy depression |
| url | https://www.mdpi.com/2673-4184/2/1/6 |
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