Validation and practical use of Plan2Heat hyperthermia treatment planning for capacitive heating
Background Capacitive devices are used for hyperthermia delivery, initially mainly in Asia, but nowadays also increasingly in Europe. Treatment planning can be very useful to determine the most effective patient-specific treatment set-up. This paper provides a validation of GPU-based simulations usi...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2022.2093996 |
| _version_ | 1818478148831936512 |
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| author | H. P. Kok J. Crezee |
| author_facet | H. P. Kok J. Crezee |
| author_sort | H. P. Kok |
| collection | DOAJ |
| description | Background Capacitive devices are used for hyperthermia delivery, initially mainly in Asia, but nowadays also increasingly in Europe. Treatment planning can be very useful to determine the most effective patient-specific treatment set-up. This paper provides a validation of GPU-based simulations using Plan2Heat for capacitive hyperthermia devices.Methods Validation was first performed by comparing simulations with an analytical solution for a spherical object placed inside a uniform electric field. Resolution was 5, 2.5 or 1 mm. Next, simulations for homogeneous and inhomogeneous phantom setups were performed for Thermotron RF8 and Celsius TCS capacitive heating devices at 2.5 mm resolution. Also different combinations of electrode sizes were evaluated. Normalized SAR profiles were compared to phantom measurements from the literature. Possible clinical use of treatment planning was demonstrated for an anal cancer patient, evaluating different treatment set-ups in prone and supine position.Results Numerical and analytical solutions showed excellent agreement. At the center of the sphere, the error was 5.1%, 2.9% and 0.2% for a resolution of 5, 2.5 and 1 mm, respectively. Comparison of measurements and simulations for both Thermotron RF8 and Celsius TCS showed very good agreement within 5% for all phantom set-ups. Simulations were capable of accurately predicting the penetration depth; a very relevant parameter for clinical application. The patient case illustrated that planning can provide insight by comparing effectiveness of different treatment strategies.Conclusion Plan2Heat can rapidly and accurately predict heating patterns generated by capacitive devices. Thus, Plan2Heat is suitable for patient-specific treatment planning for capacitive hyperthermia. |
| first_indexed | 2024-12-10T09:44:42Z |
| format | Article |
| id | doaj.art-74717ef40e3f42a0bb3156dbb7fb0499 |
| institution | Directory Open Access Journal |
| issn | 0265-6736 1464-5157 |
| language | English |
| last_indexed | 2024-12-10T09:44:42Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj.art-74717ef40e3f42a0bb3156dbb7fb04992022-12-22T01:53:52ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572022-12-0139195296610.1080/02656736.2022.2093996Validation and practical use of Plan2Heat hyperthermia treatment planning for capacitive heatingH. P. Kok0J. Crezee1Amsterdam UMC Location University of Amsterdam, Radiation Oncology, Amsterdam, The NetherlandsAmsterdam UMC Location University of Amsterdam, Radiation Oncology, Amsterdam, The NetherlandsBackground Capacitive devices are used for hyperthermia delivery, initially mainly in Asia, but nowadays also increasingly in Europe. Treatment planning can be very useful to determine the most effective patient-specific treatment set-up. This paper provides a validation of GPU-based simulations using Plan2Heat for capacitive hyperthermia devices.Methods Validation was first performed by comparing simulations with an analytical solution for a spherical object placed inside a uniform electric field. Resolution was 5, 2.5 or 1 mm. Next, simulations for homogeneous and inhomogeneous phantom setups were performed for Thermotron RF8 and Celsius TCS capacitive heating devices at 2.5 mm resolution. Also different combinations of electrode sizes were evaluated. Normalized SAR profiles were compared to phantom measurements from the literature. Possible clinical use of treatment planning was demonstrated for an anal cancer patient, evaluating different treatment set-ups in prone and supine position.Results Numerical and analytical solutions showed excellent agreement. At the center of the sphere, the error was 5.1%, 2.9% and 0.2% for a resolution of 5, 2.5 and 1 mm, respectively. Comparison of measurements and simulations for both Thermotron RF8 and Celsius TCS showed very good agreement within 5% for all phantom set-ups. Simulations were capable of accurately predicting the penetration depth; a very relevant parameter for clinical application. The patient case illustrated that planning can provide insight by comparing effectiveness of different treatment strategies.Conclusion Plan2Heat can rapidly and accurately predict heating patterns generated by capacitive devices. Thus, Plan2Heat is suitable for patient-specific treatment planning for capacitive hyperthermia.https://www.tandfonline.com/doi/10.1080/02656736.2022.2093996Capacitive heatinghyperthermia treatment planningPlan2HeatCelsius TCSThermotron RF8 |
| spellingShingle | H. P. Kok J. Crezee Validation and practical use of Plan2Heat hyperthermia treatment planning for capacitive heating International Journal of Hyperthermia Capacitive heating hyperthermia treatment planning Plan2Heat Celsius TCS Thermotron RF8 |
| title | Validation and practical use of Plan2Heat hyperthermia treatment planning for capacitive heating |
| title_full | Validation and practical use of Plan2Heat hyperthermia treatment planning for capacitive heating |
| title_fullStr | Validation and practical use of Plan2Heat hyperthermia treatment planning for capacitive heating |
| title_full_unstemmed | Validation and practical use of Plan2Heat hyperthermia treatment planning for capacitive heating |
| title_short | Validation and practical use of Plan2Heat hyperthermia treatment planning for capacitive heating |
| title_sort | validation and practical use of plan2heat hyperthermia treatment planning for capacitive heating |
| topic | Capacitive heating hyperthermia treatment planning Plan2Heat Celsius TCS Thermotron RF8 |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2022.2093996 |
| work_keys_str_mv | AT hpkok validationandpracticaluseofplan2heathyperthermiatreatmentplanningforcapacitiveheating AT jcrezee validationandpracticaluseofplan2heathyperthermiatreatmentplanningforcapacitiveheating |