Is the Depth of Invasion a Marker for Elective Neck Dissection in Early Oral Squamous Cell Carcinoma?

Is the Depth of Invasion a Marker for Elective Neck Dissection in Early Oral Squamous Cell Carcinoma?

ObjectiveThe depth of invasion (DOI) is considered an independent risk factor for occult lymph node metastasis in oral cavity squamous cell carcinoma (OCSCC). It is used to decide whether an elective neck dissection (END) is indicated in the case of a clinically negative neck for early stage carcino...

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Main Authors: Yassine Aaboubout, Quincy M. van der Toom, Maria A. J. de Ridder, Maria J. De Herdt, Berdine van der Steen, Cornelia G. F. van Lanschot, Elisa M. Barroso, Maria R. Nunes Soares, Ivo ten Hove, Hetty Mast, Roeland W. H. Smits, Aniel Sewnaik, Dominiek A. Monserez, Stijn Keereweer, Peter J. Caspers, Robert J. Baatenburg de Jong, Tom C. Bakker Schut, Gerwin J. Puppels, José A. Hardillo, Senada Koljenović
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
oral cancer
squamous cell carcinoma of head and neck
depth of invasion
occult metastasis
elective neck dissection
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.628320/full

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