| Summary: | Cousinia is one of the widespread genera of Asteraceae family.
According to previous studies on some Cousinia
species it was found that these species are rich of triterpenes,
sesquiterpenes, flavonoids, acetylenes and steroids. According to our
knowledge, there are no published reports on the chemical composition of C. iconica Hub. - Mor. and C. aintabensis Boiss. & Hausskn.,
thus we aimed to investigate secondary metabolites of these species. In this
study, the phytochemical constituents of these
species were evaluated. Seven of identified compounds were quantified. The
quantitative and qualitative determination of compounds within the extracts was
carried out by LC-MS/MS. Phytochemical
analyses revealed the presence of flavonoids, saponins, terpenes and steroids.
Preliminary examination of the mass spectrums revealed the presence of phenolic
acids and derivatives and flavonoid compounds in extracts. According to
quantitative analyses the main compound of C.
iconica (CI) and C. aintabensis (CA) extracts was rutin
with the highest contents (169.779 µg/mgextract and 161.638 µg/mgextract).
Moreover, qualitative and quantitative study combined
with different biological activities will shed new lights to the advanced
studies.
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