Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) trial

Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) trial

Chagas cardiomyopathy is the most frequent and most severe manifestation of chronic Chagas disease, and is one of the leading causes of morbidity and death in Latin America. Although the pathogenesis of Chagas cardiomyopathy is incompletely understood, it may involve several mechanisms, including pa...

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Bibliographic Details
Main Authors: Anis Rassi Jr, José Antonio Marin Neto, Anis Rassi
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ)
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
chronic Chagas cardiomyopathy
Chagas heart disease
pathogenesis
aetiological treatment
Benznidazole
BENEFIT trial
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000300224&lng=en&tlng=en

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