The performance of the Nottingham Prognosis Index and the adjuvant online decision making tool for prognosis in early-stage breast cancer patients
Background: Prognostic tools are widely used in the practice of Oncology and have been developed to help stratify patients into specific risk-related grouping. We sought to apply of two such tools used for patients with early-stage breast cancer and to correlate them with actual outcomes. Methods:...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | International Journal of Preventive Medicine |
| Subjects: | |
| Online Access: | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2015;volume=6;issue=1;spage=93;epage=93;aulast=Rejali |
| _version_ | 1828529527916068864 |
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| author | Mehri Rejali Mehdi Tazhibi Fariborz Mokarian Nazjamal Gharanjik Reyhane Mokarian |
| author_facet | Mehri Rejali Mehdi Tazhibi Fariborz Mokarian Nazjamal Gharanjik Reyhane Mokarian |
| author_sort | Mehri Rejali |
| collection | DOAJ |
| description | Background: Prognostic tools are widely used in the practice of Oncology and have been developed to help stratify patients into specific risk-related grouping. We sought to apply of two such tools used for patients with early-stage breast cancer and to correlate them with actual outcomes.
Methods: A retrospective study was designed to include early-stage breast cancer cases seen from 1994 to 2014 at the Seyedoshohada Hospital in Isfahan, Iran. Information was derived from the patients′ records, and indices were derived from prognostic tools. Information was analyzed using descriptive statistics and one sample t-test.
Results: In 233 patients, the difference between the predicted overall survival (OS) by the Adjuvant Online (AO) prognosis tools (69.28) and the observed OS (71.2) was not statistically significant (P = 0.52), and the AO prognosis tools had predicted the patients′ OS correctly. In the Nottingham prognosis index (NPI), this difference in all groups except the very poor prognosis group was not statistically significant.
Conclusions: Adjuvant Online prognosis tools were capable of predicting the 10-year OS rate although not in all of the subgroups. The NPI was capable of distinguishing good, moderate, and poor survival rates, but this ability was not visible in more specific groups with moderate and poor prognosis. |
| first_indexed | 2024-12-11T22:10:07Z |
| format | Article |
| id | doaj.art-747c2cbcac9b4faea039e0283887e7a6 |
| institution | Directory Open Access Journal |
| issn | 2008-7802 2008-8213 |
| language | English |
| last_indexed | 2024-12-11T22:10:07Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Preventive Medicine |
| spelling | doaj.art-747c2cbcac9b4faea039e0283887e7a62022-12-22T00:48:49ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132015-01-0161939310.4103/2008-7802.166503The performance of the Nottingham Prognosis Index and the adjuvant online decision making tool for prognosis in early-stage breast cancer patientsMehri RejaliMehdi TazhibiFariborz MokarianNazjamal GharanjikReyhane MokarianBackground: Prognostic tools are widely used in the practice of Oncology and have been developed to help stratify patients into specific risk-related grouping. We sought to apply of two such tools used for patients with early-stage breast cancer and to correlate them with actual outcomes. Methods: A retrospective study was designed to include early-stage breast cancer cases seen from 1994 to 2014 at the Seyedoshohada Hospital in Isfahan, Iran. Information was derived from the patients′ records, and indices were derived from prognostic tools. Information was analyzed using descriptive statistics and one sample t-test. Results: In 233 patients, the difference between the predicted overall survival (OS) by the Adjuvant Online (AO) prognosis tools (69.28) and the observed OS (71.2) was not statistically significant (P = 0.52), and the AO prognosis tools had predicted the patients′ OS correctly. In the Nottingham prognosis index (NPI), this difference in all groups except the very poor prognosis group was not statistically significant. Conclusions: Adjuvant Online prognosis tools were capable of predicting the 10-year OS rate although not in all of the subgroups. The NPI was capable of distinguishing good, moderate, and poor survival rates, but this ability was not visible in more specific groups with moderate and poor prognosis.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2015;volume=6;issue=1;spage=93;epage=93;aulast=RejaliEarly-stage breast cancerNottingham prognostic indexprognostic tools |
| spellingShingle | Mehri Rejali Mehdi Tazhibi Fariborz Mokarian Nazjamal Gharanjik Reyhane Mokarian The performance of the Nottingham Prognosis Index and the adjuvant online decision making tool for prognosis in early-stage breast cancer patients International Journal of Preventive Medicine Early-stage breast cancer Nottingham prognostic index prognostic tools |
| title | The performance of the Nottingham Prognosis Index and the adjuvant online decision making tool for prognosis in early-stage breast cancer patients |
| title_full | The performance of the Nottingham Prognosis Index and the adjuvant online decision making tool for prognosis in early-stage breast cancer patients |
| title_fullStr | The performance of the Nottingham Prognosis Index and the adjuvant online decision making tool for prognosis in early-stage breast cancer patients |
| title_full_unstemmed | The performance of the Nottingham Prognosis Index and the adjuvant online decision making tool for prognosis in early-stage breast cancer patients |
| title_short | The performance of the Nottingham Prognosis Index and the adjuvant online decision making tool for prognosis in early-stage breast cancer patients |
| title_sort | performance of the nottingham prognosis index and the adjuvant online decision making tool for prognosis in early stage breast cancer patients |
| topic | Early-stage breast cancer Nottingham prognostic index prognostic tools |
| url | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2015;volume=6;issue=1;spage=93;epage=93;aulast=Rejali |
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