Outcomes of percutaneous coronary intervention of chronic total occlusions in heart transplant recipients
ABSTRACT Introduction and objectives: Chronic total coronary occlusion (CTO) of coronary arteries is frequent in heart transplant recipients (HTR). It is usually managed with medical therapy due to the suboptimal results shown by the percutaneous coronary intervention (PCI). Although the PCI of nati...
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| Format: | Article |
| Language: | English |
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Permanyer
2019-08-01
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| Series: | REC: Interventional Cardiology (English Ed.) |
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| Online Access: | https://recintervcardiol.org/en/index.php?option=com_content&view=article&id=168 |
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| author | Jorge Solano-López Morel José A. Fernández-Díaz Victoria Martin-Yuste Manel Sabaté Tenas Juan F. Oteo-Domínguez Arturo García-Touchard Rodrigo Estévez Loureiro Javier Segovia Cubero Francisco José Hernández Pérez Ana Blasco Lobo Luis Alonso-Pulpón Javier Goicolea-Ruigómez |
| author_facet | Jorge Solano-López Morel José A. Fernández-Díaz Victoria Martin-Yuste Manel Sabaté Tenas Juan F. Oteo-Domínguez Arturo García-Touchard Rodrigo Estévez Loureiro Javier Segovia Cubero Francisco José Hernández Pérez Ana Blasco Lobo Luis Alonso-Pulpón Javier Goicolea-Ruigómez |
| author_sort | Jorge Solano-López Morel |
| collection | DOAJ |
| description | ABSTRACT Introduction and objectives: Chronic total coronary occlusion (CTO) of coronary arteries is frequent in heart transplant recipients (HTR). It is usually managed with medical therapy due to the suboptimal results shown by the percutaneous coronary intervention (PCI). Although the PCI of native CTOs is performed in experienced centres, in HTR we do not know PCI results or clinical efficacy. This is the first study ever to actually analyse the PCI-Target Lesion Procedure Success of CTO PCI and its angiographic and clinical follow-up in HTR. In addition, we compared the clinical follow-up of CTO vs non-CTO PCI in HTR. Methods: We retrospectively analysed the baseline characteristics, procedural outcomes and clinical events during the follow-up of HTR with CTO undergoing PCI between January 1, 2006 and December 31, 2016 in 2 centres with an ongoing CTO program. Over the same period, we also compared clinical events during the follow-up of these patients vs PCI on non-CTO stenosis in HTR at one of the centres. Results: PCI was successful in 13 out of 14 patients. A systematic follow-up angiography was conducted at centre 1 (n = 10). Two patients showed in-stent restenosis (20%), and a new PCI was performed successfully in both cases. Mortality rate was 28.5%, after a median follow-up of 33.5 months [interquartile range, 20-50]. We found no statistical differences in the clinical events after the PCI of CTO lesions vs non-CTO lesions in HTR. Conclusions: The PCI of CTO in HTR is feasible in experienced centres and selected patients, with a high success rate and low rate of intraprocedural complications. |
| first_indexed | 2024-12-17T10:10:26Z |
| format | Article |
| id | doaj.art-747d3b500e2e42b5a0ed07d25cac9558 |
| institution | Directory Open Access Journal |
| issn | 2604-7322 |
| language | English |
| last_indexed | 2024-12-17T10:10:26Z |
| publishDate | 2019-08-01 |
| publisher | Permanyer |
| record_format | Article |
| series | REC: Interventional Cardiology (English Ed.) |
| spelling | doaj.art-747d3b500e2e42b5a0ed07d25cac95582022-12-21T21:53:02ZengPermanyerREC: Interventional Cardiology (English Ed.)2604-73222019-08-011315216010.24875/RECICE.M19000035Outcomes of percutaneous coronary intervention of chronic total occlusions in heart transplant recipientsJorge Solano-López Morel0José A. Fernández-Díaz1Victoria Martin-Yuste2Manel Sabaté Tenas3Juan F. Oteo-Domínguez4Arturo García-Touchard5Rodrigo Estévez Loureiro6Javier Segovia Cubero7Francisco José Hernández Pérez8Ana Blasco Lobo9Luis Alonso-Pulpón10Javier Goicolea-Ruigómez11Servicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, SpainServicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, SpainServicio de Cardiología, Hospital Universitario Clínic, Barcelona, SpainServicio de Cardiología, Hospital Universitario Clínic, Barcelona, SpainServicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, SpainServicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, SpainServicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, SpainServicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, SpainServicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, SpainServicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, SpainServicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, SpainServicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, SpainABSTRACT Introduction and objectives: Chronic total coronary occlusion (CTO) of coronary arteries is frequent in heart transplant recipients (HTR). It is usually managed with medical therapy due to the suboptimal results shown by the percutaneous coronary intervention (PCI). Although the PCI of native CTOs is performed in experienced centres, in HTR we do not know PCI results or clinical efficacy. This is the first study ever to actually analyse the PCI-Target Lesion Procedure Success of CTO PCI and its angiographic and clinical follow-up in HTR. In addition, we compared the clinical follow-up of CTO vs non-CTO PCI in HTR. Methods: We retrospectively analysed the baseline characteristics, procedural outcomes and clinical events during the follow-up of HTR with CTO undergoing PCI between January 1, 2006 and December 31, 2016 in 2 centres with an ongoing CTO program. Over the same period, we also compared clinical events during the follow-up of these patients vs PCI on non-CTO stenosis in HTR at one of the centres. Results: PCI was successful in 13 out of 14 patients. A systematic follow-up angiography was conducted at centre 1 (n = 10). Two patients showed in-stent restenosis (20%), and a new PCI was performed successfully in both cases. Mortality rate was 28.5%, after a median follow-up of 33.5 months [interquartile range, 20-50]. We found no statistical differences in the clinical events after the PCI of CTO lesions vs non-CTO lesions in HTR. Conclusions: The PCI of CTO in HTR is feasible in experienced centres and selected patients, with a high success rate and low rate of intraprocedural complications.https://recintervcardiol.org/en/index.php?option=com_content&view=article&id=168Chronic total coronary occlusion Heart transplantation Coronary angioplasty Cardiac allograft vasculopathy Results |
| spellingShingle | Jorge Solano-López Morel José A. Fernández-Díaz Victoria Martin-Yuste Manel Sabaté Tenas Juan F. Oteo-Domínguez Arturo García-Touchard Rodrigo Estévez Loureiro Javier Segovia Cubero Francisco José Hernández Pérez Ana Blasco Lobo Luis Alonso-Pulpón Javier Goicolea-Ruigómez Outcomes of percutaneous coronary intervention of chronic total occlusions in heart transplant recipients REC: Interventional Cardiology (English Ed.) Chronic total coronary occlusion Heart transplantation Coronary angioplasty Cardiac allograft vasculopathy Results |
| title | Outcomes of percutaneous coronary intervention of chronic total occlusions in heart transplant recipients |
| title_full | Outcomes of percutaneous coronary intervention of chronic total occlusions in heart transplant recipients |
| title_fullStr | Outcomes of percutaneous coronary intervention of chronic total occlusions in heart transplant recipients |
| title_full_unstemmed | Outcomes of percutaneous coronary intervention of chronic total occlusions in heart transplant recipients |
| title_short | Outcomes of percutaneous coronary intervention of chronic total occlusions in heart transplant recipients |
| title_sort | outcomes of percutaneous coronary intervention of chronic total occlusions in heart transplant recipients |
| topic | Chronic total coronary occlusion Heart transplantation Coronary angioplasty Cardiac allograft vasculopathy Results |
| url | https://recintervcardiol.org/en/index.php?option=com_content&view=article&id=168 |
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