Development of quality control parameters for the standardization of bark of Ficus arnottiana Miq. (M)

Objective: To develop a novel standardization technique, which can pave the way for rapid determination of different phytoconstitutents of Ficus arnottiana (F. arnottiana). Miq. (Moraceae). From extensive literature survey it was revealed that no reports were available on, standardization parameters...

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Bibliographic Details
Main Authors: Ramandeep Singh, Ashraf Ali, G. Jeyabalan, Yogesh Kumar, Alok Semwal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Acute Disease
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Online Access:http://www.sciencedirect.com/science/article/pii/S2221618913601304
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Summary:Objective: To develop a novel standardization technique, which can pave the way for rapid determination of different phytoconstitutents of Ficus arnottiana (F. arnottiana). Miq. (Moraceae). From extensive literature survey it was revealed that no reports were available on, standardization parameters of F. arnottiana Miq. Methods: Phytochemical test, TLC analysis, foreign matter, Ash values, swelling index, foaming index, fluorescence analysis, determination of pH, extractive value, moisture content, microbiological analysis and crude fibre content were performed in the present investigation for the quality control of the drug. Results: Thus it was thought worthwhile to explore this endangered plant on the basis of its standardization parameters. Alkaloids, saponins, steroid, flavanoids and tannins were found to be present in F. arnottiana Miq. extracts. Ash value, acid insoluble ash value, water insoluble ash value, pH determination, Swelling index, foaming index and loss on drying were found to be 2.44%w/w, 0.32%w/w, 1.93%w/w, 8.29, (3.50±0.23), 1 cm, 11.6%w/w. The study will provide referential information for the correct identification of the crude drug. Conclusion: These physicochemical data and phytochemical analysis of different extracts of F. arnottiana Miq is useful for further studies for pharmacological screening. In future this study will be helpful for qualitative & quantitative analysis of phytoconstitutes for isolation of newer molecule from F. arnottiana Miq.
ISSN:2221-6189