Case Report: Respiratory paralysis associated with polymyxin B therapy

Case Report: Respiratory paralysis associated with polymyxin B therapy

Polymyxin B (PMB) and colistin are bactericidal polypeptide antibiotics discovered in 1947 and 1949 for the treatment of gram-negative bacterial infections. Polymyxin was used clinically in the 1950s, but it was gradually replaced by other antibiotics in the 1980s because of its high nephrotoxicity...

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Bibliographic Details
Main Authors: Yachan Ning, Yanqi Chu, You Wu, Ying Huang, Chunmei Wang, Li Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
respiratory paralysis
neurotoxicity
neuromuscular blockage
polymyxin B
colistin
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.963140/full

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