Protective Effects of Fucoidan on Aβ25–35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice

Protective Effects of Fucoidan on Aβ25–35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice

Alzheimer’s disease (AD) is a chronic neurodegenerative disease which contributes to memory loss and cognitive decline in the elderly. Fucoidan, extracted from brown algae, is a complex sulfated polysaccharide and potential bioactive compound. In this study, we investigated whether fucoidan protects...

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Bibliographic Details
Main Authors: Hengyun Wei, Zixiang Gao, Luping Zheng, Cuili Zhang, Zundong Liu, Yazong Yang, Hongming Teng, Lin Hou, Yuling Yin, Xiangyang Zou
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Marine Drugs
Subjects:
fucoidan
Alzheimer’s disease
neuroprotection
apoptosis
amyloid-β peptide
Online Access:http://www.mdpi.com/1660-3397/15/3/77

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