Regulation of epithelial-mesenchymal transition by protein lysine acetylation

Regulation of epithelial-mesenchymal transition by protein lysine acetylation

Abstract The epithelial-mesenchymal transition (EMT) is a vital driver of tumor progression. It is a well-known and complex trans-differentiation process in which epithelial cells undergo morphogenetic changes with loss of apical-basal polarity, but acquire spindle-shaped mesenchymal phenotypes. Lys...

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Bibliographic Details
Main Authors: Fanyun Kong, Lihong Ma, Xing Wang, Hongjuan You, Kuiyang Zheng, Renxian Tang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Cell Communication and Signaling
Subjects:
Epithelial-mesenchymal transition
Lysine acetylation
Histone
Non-histone protein
Therapy
Online Access:https://doi.org/10.1186/s12964-022-00870-y

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