Hyperosmolar expansion medium improves nucleus pulposus cell phenotype

Hyperosmolar expansion medium improves nucleus pulposus cell phenotype

Abstract Background Repopulating the degenerated intervertebral disc (IVD) with tissue‐specific nucleus pulposus cells (NPCs) has already been shown to promote regeneration in various species. Yet the applicability of NPCs as cell‐based therapy has been hampered by the low cell numbers that can be e...

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Bibliographic Details
Main Authors: Lisanne T. Laagland, Frances C. Bach, Laura B. Creemers, Christine L. Le Maitre, Deepani W. Poramba‐Liyanage, Marianna A. Tryfonidou
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:JOR Spine
Subjects:
cell‐based therapy
intervertebral disc
lower back pain
nucleus pulposus
osmolarity
regeneration
Online Access:https://doi.org/10.1002/jsp2.1219

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