Evaluation of Virulence in Cynomolgus Macaques Using a Virus Preparation Enriched for the Extracellular Form of Monkeypox Virus

Evaluation of Virulence in Cynomolgus Macaques Using a Virus Preparation Enriched for the Extracellular Form of Monkeypox Virus

The 2022 global human monkeypox outbreak emphasizes the importance of maintaining poxvirus research, including enriching a basic understanding of animal models for developing and advancing therapeutics and vaccines. Intravenous administration of monkeypox virus in macaques is arguably one of the bes...

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Bibliographic Details
Main Authors: Eric M. Mucker, Josh D. Shamblin, Arthur J. Goff, Todd M. Bell, Christopher Reed, Nancy A. Twenhafel, Jennifer Chapman, Marc Mattix, Derron Alves, Robert F. Garry, Lisa E. Hensley
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Viruses
Subjects:
orthopoxvirus
extracellular virion
nonhuman primates
viremia
model
smallpox
Online Access:https://www.mdpi.com/1999-4915/14/9/1993

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