Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings
Chronic pulmonary aspergillosis (CPA) is a recognized complication of pulmonary tuberculosis (TB). In 2015, the World Health Organization reported 2.2 million new cases of nonbacteriologically confirmed pulmonary TB; some of these patients probably had undiagnosed CPA. In October 2016, the Global Ac...
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Format: | Article |
Language: | English |
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Centers for Disease Control and Prevention
2018-08-01
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Series: | Emerging Infectious Diseases |
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Online Access: | https://wwwnc.cdc.gov/eid/article/24/8/17-1312_article |
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author | David W. Denning Iain D. Page Jeremiah Chakaya Kauser Jabeen Cecilia M. Jude Muriel Cornet Ana Alastruey-Izquierdo Felix Bongomin Paul Bowyer Arunaloke Chakrabarti Sara Gago John Guto Bruno Hochhegger Martin Hoenigl Muhammad Irfan Nicholas Irurhe Koichi Izumikawa Bruce Kirenga Veronica Manduku Samihah Moazam Rita O. Oladele Malcolm D. Richardson Juan Luis Rodriguez Tudela Anna Rozaliyani Helmut J.F. Salzer Richard Sawyer Nasilele F. Simukulwa Alena Skrahina Charlotte Sriruttan Findra Setianingrum Bayu A.P. Wilopo Donald C. Cole Haileyesus Getahun |
author_facet | David W. Denning Iain D. Page Jeremiah Chakaya Kauser Jabeen Cecilia M. Jude Muriel Cornet Ana Alastruey-Izquierdo Felix Bongomin Paul Bowyer Arunaloke Chakrabarti Sara Gago John Guto Bruno Hochhegger Martin Hoenigl Muhammad Irfan Nicholas Irurhe Koichi Izumikawa Bruce Kirenga Veronica Manduku Samihah Moazam Rita O. Oladele Malcolm D. Richardson Juan Luis Rodriguez Tudela Anna Rozaliyani Helmut J.F. Salzer Richard Sawyer Nasilele F. Simukulwa Alena Skrahina Charlotte Sriruttan Findra Setianingrum Bayu A.P. Wilopo Donald C. Cole Haileyesus Getahun |
author_sort | David W. Denning |
collection | DOAJ |
description | Chronic pulmonary aspergillosis (CPA) is a recognized complication of pulmonary tuberculosis (TB). In 2015, the World Health Organization reported 2.2 million new cases of nonbacteriologically confirmed pulmonary TB; some of these patients probably had undiagnosed CPA. In October 2016, the Global Action Fund for Fungal Infections convened an international expert panel to develop a case definition of CPA for resource-constrained settings. This panel defined CPA as illness for >3 months and all of the following: 1) weight loss, persistent cough, and/or hemoptysis; 2) chest images showing progressive cavitary infiltrates and/or a fungal ball and/or pericavitary fibrosis or infiltrates or pleural thickening; and 3) a positive Aspergillus IgG assay result or other evidence of Aspergillus infection. The proposed definition will facilitate advancements in research, practice, and policy in lower- and middle-income countries as well as in resource-constrained settings. |
first_indexed | 2024-12-12T18:23:01Z |
format | Article |
id | doaj.art-748b814c57044f61831ad11abd3642f3 |
institution | Directory Open Access Journal |
issn | 1080-6040 1080-6059 |
language | English |
last_indexed | 2024-12-12T18:23:01Z |
publishDate | 2018-08-01 |
publisher | Centers for Disease Control and Prevention |
record_format | Article |
series | Emerging Infectious Diseases |
spelling | doaj.art-748b814c57044f61831ad11abd3642f32022-12-22T00:16:06ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592018-08-0124810.3201/eid2408.171312Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained SettingsDavid W. DenningIain D. PageJeremiah ChakayaKauser JabeenCecilia M. JudeMuriel CornetAna Alastruey-IzquierdoFelix BongominPaul BowyerArunaloke ChakrabartiSara GagoJohn GutoBruno HochheggerMartin HoeniglMuhammad IrfanNicholas IrurheKoichi IzumikawaBruce KirengaVeronica MandukuSamihah MoazamRita O. OladeleMalcolm D. RichardsonJuan Luis Rodriguez TudelaAnna RozaliyaniHelmut J.F. SalzerRichard SawyerNasilele F. SimukulwaAlena SkrahinaCharlotte SriruttanFindra SetianingrumBayu A.P. WilopoDonald C. ColeHaileyesus GetahunChronic pulmonary aspergillosis (CPA) is a recognized complication of pulmonary tuberculosis (TB). In 2015, the World Health Organization reported 2.2 million new cases of nonbacteriologically confirmed pulmonary TB; some of these patients probably had undiagnosed CPA. In October 2016, the Global Action Fund for Fungal Infections convened an international expert panel to develop a case definition of CPA for resource-constrained settings. This panel defined CPA as illness for >3 months and all of the following: 1) weight loss, persistent cough, and/or hemoptysis; 2) chest images showing progressive cavitary infiltrates and/or a fungal ball and/or pericavitary fibrosis or infiltrates or pleural thickening; and 3) a positive Aspergillus IgG assay result or other evidence of Aspergillus infection. The proposed definition will facilitate advancements in research, practice, and policy in lower- and middle-income countries as well as in resource-constrained settings.https://wwwnc.cdc.gov/eid/article/24/8/17-1312_articleTuberculosisAspergillusantibodyaspergillomaimagingdeveloping countries |
spellingShingle | David W. Denning Iain D. Page Jeremiah Chakaya Kauser Jabeen Cecilia M. Jude Muriel Cornet Ana Alastruey-Izquierdo Felix Bongomin Paul Bowyer Arunaloke Chakrabarti Sara Gago John Guto Bruno Hochhegger Martin Hoenigl Muhammad Irfan Nicholas Irurhe Koichi Izumikawa Bruce Kirenga Veronica Manduku Samihah Moazam Rita O. Oladele Malcolm D. Richardson Juan Luis Rodriguez Tudela Anna Rozaliyani Helmut J.F. Salzer Richard Sawyer Nasilele F. Simukulwa Alena Skrahina Charlotte Sriruttan Findra Setianingrum Bayu A.P. Wilopo Donald C. Cole Haileyesus Getahun Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings Emerging Infectious Diseases Tuberculosis Aspergillus antibody aspergilloma imaging developing countries |
title | Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings |
title_full | Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings |
title_fullStr | Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings |
title_full_unstemmed | Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings |
title_short | Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings |
title_sort | case definition of chronic pulmonary aspergillosis in resource constrained settings |
topic | Tuberculosis Aspergillus antibody aspergilloma imaging developing countries |
url | https://wwwnc.cdc.gov/eid/article/24/8/17-1312_article |
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