Transferrin Biosynthesized in the Brain Is a Novel Biomarker for Alzheimer’s Disease

Transferrin Biosynthesized in the Brain Is a Novel Biomarker for Alzheimer’s Disease

Glycosylation is a cell type-specific post-translational modification that can be used for biomarker identification in various diseases. Aim of this study is to explore glycan-biomarkers on transferrin (Tf) for Alzheimer’s disease (AD) in cerebrospinal fluid (CSF). Glycan structures of CSF Tf were a...

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Bibliographic Details
Main Authors: Kyoka Hoshi, Hiromi Ito, Eriko Abe, Takashi J. Fuwa, Mayumi Kanno, Yuta Murakami, Mitsunari Abe, Takenobu Murakami, Akioh Yoshihara, Yoshikazu Ugawa, Takashi Saito, Takaomi C. Saido, Kana Matsumoto, Yoshiki Yamaguchi, Katsutoshi Furukawa, Hiroyuki Arai, Mitsuyasu Kanai, Masakazu Miyajima, Hajime Arai, Norihiro Ogawa, Hiroyasu Akatsu, Yoshio Hashizume, Hiroaki Tateno, Takashi Honda, Yasuhiro Hashimoto
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Metabolites
Subjects:
Alzheimer’s disease
cerebrospinal fluid
biomarker
transferrin
glycan-isoforms
Online Access:https://www.mdpi.com/2218-1989/11/9/616

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https://www.mdpi.com/2218-1989/11/9/616

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