A Comparison of Functional Networks Derived From Representational Similarity, Functional Connectivity, and Univariate Analyses
The invention of representational similarity analysis [RSA, following multi-voxel pattern analysis (MVPA)] has allowed cognitive neuroscientists to identify the representational structure of multiple brain regions, moving beyond functional localization. By comparing these structures, cognitive neuro...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2020-01-01
|
| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fnins.2019.01348/full |
| _version_ | 1818175212766625792 |
|---|---|
| author | Ineke Pillet Hans Op de Beeck Haemy Lee Masson |
| author_facet | Ineke Pillet Hans Op de Beeck Haemy Lee Masson |
| author_sort | Ineke Pillet |
| collection | DOAJ |
| description | The invention of representational similarity analysis [RSA, following multi-voxel pattern analysis (MVPA)] has allowed cognitive neuroscientists to identify the representational structure of multiple brain regions, moving beyond functional localization. By comparing these structures, cognitive neuroscientists can characterize how brain areas form functional networks. Univariate analysis (UNIVAR) and functional connectivity analysis (FCA) are two other popular methods to identify functional networks. Despite their popularity, few studies have examined the relationship between networks from RSA with those from UNIVAR and FCA. Thus, the aim of the current study is to examine the similarities between neural networks derived from RSA with those from UNIVAR and FCA to explore how these methods relate to each other. We analyzed the data of a previously published study with the three methods and compared the results by performing (partial) correlation and multiple regression analysis. Our findings reveal that neural networks resulting from RSA, UNIVAR, and FCA methods are highly similar to each other even after ruling out the effect of anatomical proximity between the network nodes. Nevertheless, the neural network from each method shows unique organization that cannot be explained by any of the other methods. Thus, we conclude that the RSA, UNIVAR and FCA methods provide similar but not identical information on how brain regions are organized in functional networks. |
| first_indexed | 2024-12-11T19:56:43Z |
| format | Article |
| id | doaj.art-749045f059ee4a60b4627f3f0781b743 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-11T19:56:43Z |
| publishDate | 2020-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-749045f059ee4a60b4627f3f0781b7432022-12-22T00:52:37ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2020-01-011310.3389/fnins.2019.01348464352A Comparison of Functional Networks Derived From Representational Similarity, Functional Connectivity, and Univariate AnalysesIneke PilletHans Op de BeeckHaemy Lee MassonThe invention of representational similarity analysis [RSA, following multi-voxel pattern analysis (MVPA)] has allowed cognitive neuroscientists to identify the representational structure of multiple brain regions, moving beyond functional localization. By comparing these structures, cognitive neuroscientists can characterize how brain areas form functional networks. Univariate analysis (UNIVAR) and functional connectivity analysis (FCA) are two other popular methods to identify functional networks. Despite their popularity, few studies have examined the relationship between networks from RSA with those from UNIVAR and FCA. Thus, the aim of the current study is to examine the similarities between neural networks derived from RSA with those from UNIVAR and FCA to explore how these methods relate to each other. We analyzed the data of a previously published study with the three methods and compared the results by performing (partial) correlation and multiple regression analysis. Our findings reveal that neural networks resulting from RSA, UNIVAR, and FCA methods are highly similar to each other even after ruling out the effect of anatomical proximity between the network nodes. Nevertheless, the neural network from each method shows unique organization that cannot be explained by any of the other methods. Thus, we conclude that the RSA, UNIVAR and FCA methods provide similar but not identical information on how brain regions are organized in functional networks.https://www.frontiersin.org/article/10.3389/fnins.2019.01348/fullfMRImulti-voxel pattern analysis (MVPA)representational similarity analysis (RSA)univariate analysisfunctional connectivity (FC) |
| spellingShingle | Ineke Pillet Hans Op de Beeck Haemy Lee Masson A Comparison of Functional Networks Derived From Representational Similarity, Functional Connectivity, and Univariate Analyses Frontiers in Neuroscience fMRI multi-voxel pattern analysis (MVPA) representational similarity analysis (RSA) univariate analysis functional connectivity (FC) |
| title | A Comparison of Functional Networks Derived From Representational Similarity, Functional Connectivity, and Univariate Analyses |
| title_full | A Comparison of Functional Networks Derived From Representational Similarity, Functional Connectivity, and Univariate Analyses |
| title_fullStr | A Comparison of Functional Networks Derived From Representational Similarity, Functional Connectivity, and Univariate Analyses |
| title_full_unstemmed | A Comparison of Functional Networks Derived From Representational Similarity, Functional Connectivity, and Univariate Analyses |
| title_short | A Comparison of Functional Networks Derived From Representational Similarity, Functional Connectivity, and Univariate Analyses |
| title_sort | comparison of functional networks derived from representational similarity functional connectivity and univariate analyses |
| topic | fMRI multi-voxel pattern analysis (MVPA) representational similarity analysis (RSA) univariate analysis functional connectivity (FC) |
| url | https://www.frontiersin.org/article/10.3389/fnins.2019.01348/full |
| work_keys_str_mv | AT inekepillet acomparisonoffunctionalnetworksderivedfromrepresentationalsimilarityfunctionalconnectivityandunivariateanalyses AT hansopdebeeck acomparisonoffunctionalnetworksderivedfromrepresentationalsimilarityfunctionalconnectivityandunivariateanalyses AT haemyleemasson acomparisonoffunctionalnetworksderivedfromrepresentationalsimilarityfunctionalconnectivityandunivariateanalyses AT inekepillet comparisonoffunctionalnetworksderivedfromrepresentationalsimilarityfunctionalconnectivityandunivariateanalyses AT hansopdebeeck comparisonoffunctionalnetworksderivedfromrepresentationalsimilarityfunctionalconnectivityandunivariateanalyses AT haemyleemasson comparisonoffunctionalnetworksderivedfromrepresentationalsimilarityfunctionalconnectivityandunivariateanalyses |